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Eri2 Gene Detail
Summary
  • Symbol
    Eri2
  • Name
    exoribonuclease 2
  • Synonyms
    4933424N09Rik, Exod1, mKIAA1504
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918401
    NCBI Gene: 71151
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:119383049-119393283 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 64.18 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    388 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918401
protein coding gene Chr7:119367902-119393283 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032918
protein coding gene Chr7:123714023-123728280 (-)
A/J MGP_AJ_G0032901
protein coding gene Chr7:120499474-120524768 (-)
AKR/J MGP_AKRJ_G0032833
protein coding gene Chr7:123609488-123637246 (-)
BALB/cJ MGP_BALBcJ_G0032906
protein coding gene Chr7:120229744-120255650 (-)
C3H/HeJ MGP_C3HHeJ_G0032616
protein coding gene Chr7:123510171-123535224 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033412
protein coding gene Chr7:128591665-128619102 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030384
protein coding gene Chr7:121933985-121959476 (-)
CAST/EiJ MGP_CASTEiJ_G0031944
protein coding gene Chr7:115278145-115290361 (-)
CBA/J MGP_CBAJ_G0032589
protein coding gene Chr7:132892392-132918045 (-)
DBA/2J MGP_DBA2J_G0032741
protein coding gene Chr7:118548591-118574090 (-)
FVB/NJ MGP_FVBNJ_G0032694
protein coding gene Chr7:118385793-118413123 (-)
LP/J MGP_LPJ_G0032835
protein coding gene Chr7:125166902-125181964 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032726
protein coding gene Chr7:134346584-134380532 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033432
protein coding gene Chr7:122583367-122610017 (-)
PWK/PhJ MGP_PWKPhJ_G0031652
protein coding gene Chr7:111463874-111490178 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031498
protein coding gene Chr7:109339205-109366905 (-)
WSB/EiJ MGP_WSBEiJ_G0032057
protein coding gene Chr7:123491033-123517030 (-)



Homology
more
  • Human Ortholog
    ERI2, ERI1 exoribonuclease family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERI2, ERI1 exoribonuclease family member 2
  • Synonyms
    EXOD1, ZGRF5
  • Links
    NCBI Gene ID: 112479
    neXtProt AC: NX_A8K979
    UniProt: A8K979

  • Chr Location
    16p12.3; chr16:20780193-20900349 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71151 NCBI Gene Model | MGI Sequence Detail 10235 C57BL/6J ±  kb
transcript NM_027698 RefSeq | MGI Sequence Detail 3569 C57BL/6  
polypeptide Q5BKS4 UniProt | EBI | MGI Sequence Detail 688 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 6
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory