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Lrrfip2 Gene Detail
Summary
  • Symbol
    Lrrfip2
  • Name
    leucine rich repeat (in FLII) interacting protein 2
  • Synonyms
    5133400F20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918518
    NCBI Gene: 71268
  • Alliance
    gene page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110946660-111054736 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.92 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2517 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918518
 protein coding gene Chr9:110946614-111054736 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035370
 protein coding gene Chr9:113333047-113451471 (+)
A/J MGP_AJ_G0035351
 protein coding gene Chr9:109188346-109302765 (+)
AKR/J MGP_AKRJ_G0035282
 protein coding gene Chr9:111914132-112027559 (+)
BALB/cJ MGP_BALBcJ_G0035346
 protein coding gene Chr9:108939646-109050726 (+)
C3H/HeJ MGP_C3HHeJ_G0035054
 protein coding gene Chr9:112413856-112527881 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035868
 protein coding gene Chr9:116457560-116567885 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032754
 protein coding gene Chr9:106393766-106501852 (+)
CAST/EiJ MGP_CASTEiJ_G0034360
 protein coding gene Chr9:112216991-112328182 (+)
CBA/J MGP_CBAJ_G0035021
 protein coding gene Chr9:120752947-120872299 (+)
DBA/2J MGP_DBA2J_G0035180
 protein coding gene Chr9:108641419-108750886 (+)
FVB/NJ MGP_FVBNJ_G0035127
 protein coding gene Chr9:107484966-107591623 (+)
LP/J MGP_LPJ_G0035259
 protein coding gene Chr9:113616377-113729869 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035167
 protein coding gene Chr9:122055614-122165666 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035888
 protein coding gene Chr9:112272088-112380049 (+)
PWK/PhJ MGP_PWKPhJ_G0034067
 protein coding gene Chr9:108894624-109004187 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033902
 protein coding gene Chr9:112360337-112470842 (+)
WSB/EiJ MGP_WSBEiJ_G0034481
 protein coding gene Chr9:112128032-112236713 (+)



Homology
more
  • Human Ortholog
    LRRFIP2, LRR binding FLII interacting protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRFIP2, LRR binding FLII interacting protein 2
  • Synonyms
    HUFI-2
  • Links
    NCBI Gene ID: 9209
    neXtProt AC: NX_Q9Y608
    UniProt: Q9Y608

  • Chr Location
    3p22.2; chr3:37052626-37183689 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    737
  • Tissues
    8
  • cDNA Data
    78
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032497 Ensembl Gene Model | MGI Sequence Detail 108077 C57BL/6J ±  kb
transcript ENSMUST00000239186 Ensembl | MGI Sequence Detail 2421 Not Applicable  
polypeptide ENSMUSP00000159250 Ensembl | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    13 Sequences
  • Protein Ontology
    PR:000009943 leucine-rich repeat flightless-interacting protein 2
    (term hierarchy)
  • InterPro Domains
    IPR019139 Leucine-rich repeat flightless-interacting protein 1/2
  • GlyGen
    Q91WK0 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 79
    cDNA 78
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143149
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:297684 Hooper JE, et al., An Alternative Splicing Program for Mouse Craniofacial Development. Front Physiol. 2020;11:1099
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory