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Noxred1 Gene Detail
Summary
  • Symbol
    Noxred1
  • Name
    NADP+ dependent oxidoreductase domain containing 1
  • Synonyms
    4933437F05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918525
    NCBI Gene: 71275
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:87267897-87285375 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 41.42 cM, cytoband E
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    426 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918525
 protein coding gene Chr12:87267814-87285506 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019982
 protein coding gene Chr12:88119896-88137633 (-)
A/J MGP_AJ_G0019940
 protein coding gene Chr12:84771519-84783803 (-)
AKR/J MGP_AKRJ_G0019915
 protein coding gene Chr12:87070426-87084533 (-)
BALB/cJ MGP_BALBcJ_G0019919
 protein coding gene Chr12:85104616-85116899 (-)
C3H/HeJ MGP_C3HHeJ_G0019725
 protein coding gene Chr12:87565064-87577360 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020371
 protein coding gene Chr12:90660769-90673263 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017989
 protein coding gene Chr12:81647827-81662603 (-)
CAST/EiJ MGP_CASTEiJ_G0019275
 protein coding gene Chr12:82587390-82605077 (-)
CBA/J MGP_CBAJ_G0019697
 protein coding gene Chr12:94134773-94147053 (-)
DBA/2J MGP_DBA2J_G0019810
 protein coding gene Chr12:84266474-84279232 (-)
FVB/NJ MGP_FVBNJ_G0019797
 protein coding gene Chr12:83260000-83277315 (-)
LP/J MGP_LPJ_G0019884
 protein coding gene Chr12:88000964-88013232 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019836
 protein coding gene Chr12:96896521-96909875 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020403
 protein coding gene Chr12:86702653-86719716 (-)
PWK/PhJ MGP_PWKPhJ_G0019039
 protein coding gene Chr12:78819409-78833237 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018834
 protein coding gene Chr12:81209822-81223641 (-)
WSB/EiJ MGP_WSBEiJ_G0019328
 protein coding gene Chr12:87476808-87489770 (-)



Homology
more
  • Human Ortholog
    NOXRED1, NADP dependent oxidoreductase domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NOXRED1, NADP dependent oxidoreductase domain containing 1
  • Synonyms
    C14orf148
  • Links
    NCBI Gene ID: 122945
    neXtProt AC: NX_Q6NXP6
    UniProt: Q6NXP6

  • Chr Location
    14q24.3; chr14:77394021-77426013 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    6
  • Targeted
    1
  • Genomic Mutations
    1 involving Noxred1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    27 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71275 NCBI Gene Model | MGI Sequence Detail 17479 C57BL/6J ±  kb
transcript NM_027744 RefSeq | MGI Sequence Detail 1412 Not Specified  
polypeptide Q9D3S5 UniProt | EBI | MGI Sequence Detail 366 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory