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Krtap2-4 Gene Detail
Summary
  • Symbol
    Krtap2-4
  • Name
    keratin associated protein 2-4
  • Synonyms
    5530401P19Rik, KAP2.4, KRTAP2.4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918703
    NCBI Gene: 71453
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99504845-99505672 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 62.96 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    143 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918703
 protein coding gene Chr11:99504843-99505672 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019105
 protein coding gene Chr11:102295046-102296886 (-)
A/J MGP_AJ_G0019075
 protein coding gene Chr11:97990560-97996800 (-)
AKR/J MGP_AKRJ_G0019045
 protein coding gene Chr11:101024105-101024946 (-)
BALB/cJ MGP_BALBcJ_G0019047
 protein coding gene Chr11:98494840-98496022 (-)
C3H/HeJ MGP_C3HHeJ_G0018861
 protein coding gene Chr11:101184070-101184911 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019497
 protein coding gene Chr11:105429604-105431923 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017132
 protein coding gene Chr11:95543724-95544545 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0018834
 protein coding gene Chr11:109823888-109827457 (-)
DBA/2J MGP_DBA2J_G0018940
 protein coding gene Chr11:97561155-97562105 (-)
FVB/NJ MGP_FVBNJ_G0018931
 protein coding gene Chr11:97059336-97060177 (-)
LP/J MGP_LPJ_G0019011
 protein coding gene Chr11:102763740-102764581 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018958
 protein coding gene Chr11:109488782-109489623 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019539
 protein coding gene Chr11:101393787-101394781 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0017974
 protein coding gene Chr11:101134291-101134925 (+)
WSB/EiJ MGP_WSBEiJ_G0018466
 protein coding gene Chr11:101356737-101358116 (-)



Homology
more
  • Human Ortholog
    KRTAP2-2, keratin associated protein 2-2
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP2-2, keratin associated protein 2-2
  • Synonyms
    KAP2.1, KAP2.2, KRTAP2-1, KRTAP2.1A, KRTAP2.1B
  • Links
    NCBI Gene ID: 728279
    neXtProt AC: NX_Q9BYT5, NX_Q9BYU5

  • Chr Location
    17q21.2; chr17:41054498-41055230 (-)  GRCh38
  • Human Ortholog
    KRTAP2-3, keratin associated protein 2-3
  • Synonyms
    KAP2.3, KAP2.4, KRTAP2.3, KRTAP2-4, KRTAP2.4
  • Links
    NCBI Gene ID: 730755
    neXtProt AC: NX_P0C7H8, NX_Q9BYR9
    UniProt: P0C7H8

  • Chr Location
    chr17:41059240-41060114 (-)  GRCh38
  • Human Ortholog
    KRTAP2-4, keratin associated protein 2-4
  • Synonyms
    KAP2.1B, KAP2.3, KAP2.4, KRTAP2-3, KRTAP2.3, KRTAP2.4
  • Links
    NCBI Gene ID: 85294
    neXtProt AC: NX_P0C7H8, NX_Q9BYR9
    UniProt: Q9BYR9

  • Chr Location
    17q21.2; chr17:41065116-41065879 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060756 Ensembl Gene Model | MGI Sequence Detail 828 C57BL/6J ±  kb
transcript ENSMUST00000074926 Ensembl | MGI Sequence Detail 828 Not Applicable  
polypeptide ENSMUSP00000074461 Ensembl | MGI Sequence Detail 131 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
    IPR052154 Keratin-associated protein type 2
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Phenotypes 7
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory