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Tmem248 Gene Detail
Summary
  • Symbol
    Tmem248
  • Name
    transmembrane protein 248
  • Synonyms
    0610007L01Rik, A930023A16Rik, G430067H08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918917
    NCBI Gene: 71667
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:130248585-130272606 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 68.91 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    619 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918917
 protein coding gene Chr5:130245922-130272606 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030143
 protein coding gene Chr5:134337230-134366350 (+)
A/J MGP_AJ_G0030111
 protein coding gene Chr5:128673911-128701412 (+)
AKR/J MGP_AKRJ_G0030044
 protein coding gene Chr5:132847665-132876646 (+)
BALB/cJ MGP_BALBcJ_G0030121
 protein coding gene Chr5:130031498-130058481 (+)
C3H/HeJ MGP_C3HHeJ_G0029837
 protein coding gene Chr5:133417318-133445764 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030574
 protein coding gene Chr5:139485350-139514889 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027799
 protein coding gene Chr5:123054018-123080073 (+)
CAST/EiJ MGP_CASTEiJ_G0029247
 protein coding gene Chr5:132737547-132765407 (+)
CBA/J MGP_CBAJ_G0029807
 protein coding gene Chr5:144918134-144947197 (+)
DBA/2J MGP_DBA2J_G0029958
 protein coding gene Chr5:128639139-128665900 (+)
FVB/NJ MGP_FVBNJ_G0029913
 protein coding gene Chr5:127731049-127758300 (+)
LP/J MGP_LPJ_G0030046
 protein coding gene Chr5:134855171-134882382 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029945
 protein coding gene Chr5:148254629-148283516 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030614
 protein coding gene Chr5:132549239-132576696 (+)
PWK/PhJ MGP_PWKPhJ_G0028961
 protein coding gene Chr5:127579379-127606577 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028797
 protein coding gene Chr5:130127155-130155577 (+)
WSB/EiJ MGP_WSBEiJ_G0029320
 protein coding gene Chr5:133259406-133287800 (+)



Homology
more
  • Human Ortholog
    TMEM248, transmembrane protein 248
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM248, transmembrane protein 248
  • Synonyms
    C7orf42
  • Links
    NCBI Gene ID: 55069
    neXtProt AC: NX_Q9NWD8
    UniProt: Q9NWD8

  • Chr Location
    7q11.21; chr7:66921225-66958551 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    33 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    34
  • cDNA Data
    132
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71667 NCBI Gene Model | MGI Sequence Detail 24022 C57BL/6J ±  kb
    transcript NM_027854 RefSeq | MGI Sequence Detail 3669 C57BL/6  
    polypeptide Q3TBN1 UniProt | EBI | MGI Sequence Detail 314 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 132
      cDNA 132

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1925210, MGI:2141241
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Gene Ontology 1
      Phenotypes 21
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory