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Cpn2 Gene Detail
Summary
  • Symbol
    Cpn2
  • Name
    carboxypeptidase N, polypeptide 2
  • Synonyms
    1300018K11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919006
    NCBI Gene: 71756
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:30075196-30086317 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 21.22 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    408 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919006
 protein coding gene Chr16:30075196-30086350 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022709
 protein coding gene Chr16:28143862-28157256 (-)
A/J MGP_AJ_G0022672
 protein coding gene Chr16:26850629-26861765 (-)
AKR/J MGP_AKRJ_G0022646
 protein coding gene Chr16:27864386-27875485 (-)
BALB/cJ MGP_BALBcJ_G0022676
 protein coding gene Chr16:27028196-27039727 (-)
C3H/HeJ MGP_C3HHeJ_G0022441
 protein coding gene Chr16:27972758-27985136 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023125
 protein coding gene Chr16:28752925-28764057 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020643
 protein coding gene Chr16:27285639-27298358 (-)
CAST/EiJ MGP_CASTEiJ_G0021969
 protein coding gene Chr16:28059111-28070268 (-)
CBA/J MGP_CBAJ_G0022411
 protein coding gene Chr16:29964444-29975865 (-)
DBA/2J MGP_DBA2J_G0022544
 protein coding gene Chr16:26730613-26741649 (-)
FVB/NJ MGP_FVBNJ_G0022519
 protein coding gene Chr16:26701083-26713408 (-)
LP/J MGP_LPJ_G0022611
 protein coding gene Chr16:27960152-27971263 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022538
 protein coding gene Chr16:29493696-29506027 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023137
 protein coding gene Chr16:27830259-27841355 (-)
PWK/PhJ MGP_PWKPhJ_G0021708
 protein coding gene Chr16:27027527-27038960 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021539
 protein coding gene Chr16:27591949-27603061 (-)
WSB/EiJ MGP_WSBEiJ_G0022013
 protein coding gene Chr16:27779325-27790435 (-)



Homology
more
  • Human Ortholog
    CPN2, carboxypeptidase N subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPN2, carboxypeptidase N subunit 2
  • Synonyms
    ACBP
  • Links
    NCBI Gene ID: 1370
    neXtProt AC: NX_P22792
    UniProt: P22792

  • Chr Location
    3q29; chr3:194339768-194351328 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    32
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023176 Ensembl Gene Model | MGI Sequence Detail 11122 C57BL/6J ±  kb
transcript ENSMUST00000064856 Ensembl | MGI Sequence Detail 4550 Not Applicable  
polypeptide ENSMUSP00000069318 Ensembl | MGI Sequence Detail 547 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005815 carboxypeptidase N subunit 2
    (term hierarchy)
  • InterPro Domains
    IPR000483 Cysteine-rich flanking region, C-terminal
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
    IPR000372 Leucine-rich repeat N-terminal domain
    IPR003591 Leucine-rich repeat, typical subtype
    IPR050328 Multifunctional Developmental and Immune Receptor
    IPR051432 Voltage and calcium-activated potassium channel auxiliary protein
  • GlyGen
    Q9DBB9 9 sites, 2 N-linked glycans (4 sites)
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265604 Naba A, et al., The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol Cell Proteomics. 2012 Apr;11(4):M111.014647
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory