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Tha1 Gene Detail
Summary
  • Symbol
    Tha1
  • Name
    threonine aldolase 1
  • Synonyms
    1300017K07Rik, GLY1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919026
    NCBI Gene: 71776
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:117758778-117764307 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 82.96 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    237 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919026
 protein coding gene Chr11:117758775-117764352 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019458
 protein coding gene Chr11:122154862-122160391 (-)
A/J MGP_AJ_G0019426
 protein coding gene Chr11:116742921-116748638 (-)
AKR/J MGP_AKRJ_G0019396
 protein coding gene Chr11:120294151-120299682 (-)
BALB/cJ MGP_BALBcJ_G0019401
 protein coding gene Chr11:117111680-117117206 (-)
C3H/HeJ MGP_C3HHeJ_G0019207
 protein coding gene Chr11:120583910-120589439 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019850
 protein coding gene Chr11:125883954-125889484 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017475
 protein coding gene Chr11:113751271-113761165 (-)
CAST/EiJ MGP_CASTEiJ_G0018761
 protein coding gene Chr11:122001415-122008137 (-)
CBA/J MGP_CBAJ_G0019178
 protein coding gene Chr11:130833843-130839370 (-)
DBA/2J MGP_DBA2J_G0019290
 protein coding gene Chr11:116141647-116147174 (-)
FVB/NJ MGP_FVBNJ_G0019282
 protein coding gene Chr11:115761301-115766828 (-)
LP/J MGP_LPJ_G0019360
 protein coding gene Chr11:122478598-122484129 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019315
 protein coding gene Chr11:129797544-129803072 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019889
 protein coding gene Chr11:120944664-120950962 (-)
PWK/PhJ MGP_PWKPhJ_G0018527
 protein coding gene Chr11:117499637-117505184 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018319
 protein coding gene Chr11:120673186-120679536 (-)
WSB/EiJ MGP_WSBEiJ_G0018813
 protein coding gene Chr11:120909988-120915514 (-)



Homology
more
  • Human Ortholog
    THA1P, threonine aldolase 1, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THA1P, threonine aldolase 1, pseudogene
  • Synonyms
    GLY1
  • Links
    NCBI Gene ID: 390816

  • Chr Location
    17q25.3; chr17:78248493-78256185 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    820
  • Tissues
    114
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000017713 Ensembl Gene Model | MGI Sequence Detail 5530 C57BL/6J ±  kb
transcript ENSMUST00000033230 Ensembl | MGI Sequence Detail 1770 Not Applicable  
polypeptide ENSMUSP00000033230 Ensembl | MGI Sequence Detail 400 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • PDB
    8PUM, 8PUS
  • InterPro Domains
    IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase
    IPR023603 Low specificity L-threonine aldolase-like
    IPR015424 Pyridoxal phosphate-dependent transferase
    IPR015421 Pyridoxal phosphate-dependent transferase, major domain
    IPR015422 Pyridoxal phosphate-dependent transferase, small domain
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 22
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory