Ranbp3 MGI Mouse Gene Detail - MGI:1919060

Symbol

Ranbp3
Name

RAN binding protein 3
Synonyms

2610024N24Rik

Feature Type

protein coding gene
IDs

MGI:1919060
NCBI Gene: 71810
Alliance

gene page
Transcription Start Sites

14 TSS

Sequence Map

Chr17:56980294-57018764 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 17, 29.45 cM, cytoband D
Mapping Data

3 experiments

SNPs within 2kb

671 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919060	protein coding gene	Chr17:56980225-57018769 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0023934	protein coding gene	Chr17:58386427-58424862 (+)
A/J	MGP_AJ_G0023892	protein coding gene	Chr17:56787953-56827073 (+)
AKR/J	MGP_AKRJ_G0023861	protein coding gene	Chr17:57490038-57532355 (+)
BALB/cJ	MGP_BALBcJ_G0023893	protein coding gene	Chr17:56605511-56645266 (+)
C3H/HeJ	MGP_C3HHeJ_G0023657	protein coding gene	Chr17:58222598-58266062 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024339	protein coding gene	Chr17:60648899-60688599 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0021785	protein coding gene	Chr17:53261668-53300410 (+)
CAST/EiJ	MGP_CASTEiJ_G0023139	protein coding gene	Chr17:58501365-58541990 (+)
CBA/J	MGP_CBAJ_G0023633	protein coding gene	Chr17:63019343-63067201 (+)
DBA/2J	MGP_DBA2J_G0023761	protein coding gene	Chr17:55486917-55526401 (+)
FVB/NJ	MGP_FVBNJ_G0023727	protein coding gene	Chr17:55033492-55079392 (+)
LP/J	MGP_LPJ_G0023843	protein coding gene	Chr17:59071564-59113905 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0023755	protein coding gene	Chr17:62504847-62544901 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024383	protein coding gene	Chr17:57855634-57898353 (+)
PWK/PhJ	MGP_PWKPhJ_G0022885	protein coding gene	Chr17:54846428-54885520 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0022696	protein coding gene	Chr17:54623558-54663225 (+)
WSB/EiJ	MGP_WSBEiJ_G0023205	protein coding gene	Chr17:58471026-58511545 (+)

Human Ortholog

RANBP3, RAN binding protein 3

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RANBP3, RAN binding protein 3
Links

HGNC:9850

NCBI Gene ID: 8498

neXtProt AC: NX_Q9H6Z4

UniProt: Q9H6Z4
Chr Location

19p13.3; chr19:5916139-5978142 (-) GRCh38

MGI Vertebrate Homology

Ranbp3 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: RANBP3
Gene Tree

Ranbp3

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

42
Endonuclease-mediated

3
Gene trapped

37
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

47 strains or lines available

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All GO Annotations

8
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

728
Tissues

22
cDNA Data

13
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ranbp3

ZFIN ranbp3b

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All Sequences

95
RefSeq

33
UniProt

2
CCDS

CCDS28911.1, CCDS89127.1

Ensembl

ENSMUSG00000002372 (Evidence)
NCBI Gene

71810

			Length	Strain/Species	Flank
genomic	ENSMUSG00000002372	Ensembl Gene Model \| MGI Sequence Detail	38471	C57BL/6J	± kb
transcript	ENSMUST00000233319	Ensembl \| MGI Sequence Detail	2567	Not Applicable
polypeptide	ENSMUSP00000156588	Ensembl \| MGI Sequence Detail	558	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000013713 Ran-binding protein 3

(term hierarchy)
InterPro Domains

IPR011993 PH-like domain superfamily

IPR000156 Ran binding domain

IPR045255 Ran binding protein RanBP1-like
GlyGen

Q9CT10 1 site, 1 O-linked glycan (1 site)

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All nucleic 16

Genomic 2

cDNA 13

Primer pair 1

Microarray probesets 4

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MGI:2146749

Summaries

All 39

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 14
Earliest

J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Ranbp3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr145322	Chr17:56980223-56980232 (+)	-66 bp
Tssr145323	Chr17:56980273-56980287 (+)	-14 bp
Tssr145324	Chr17:56980321-56980328 (+)	31 bp
Tssr145325	Chr17:56980356-56980392 (+)	80 bp
Tssr145326	Chr17:56987545-56987552 (+)	7,255 bp
Tssr145327	Chr17:57003727-57003749 (+)	23,444 bp
Tssr145328	Chr17:57015858-57015868 (+)	35,569 bp
Tssr145329	Chr17:57016906-57016934 (+)	36,626 bp
Tssr145330	Chr17:57016936-57016975 (+)	36,662 bp
Tssr145331	Chr17:57016981-57016992 (+)	36,693 bp
Tssr145332	Chr17:57017004-57017017 (+)	36,717 bp
Tssr145333	Chr17:57017028-57017039 (+)	36,740 bp
Tssr145334	Chr17:57017064-57017071 (+)	36,774 bp
Tssr145335	Chr17:57017942-57017954 (+)	37,654 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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