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Kif23 Gene Detail
Summary
  • Symbol
    Kif23
  • Name
    kinesin family member 23
  • Synonyms
    3110001D19Rik, C87313, CHO1, Knsl5, MKLP-1, MKLP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919069
    NCBI Gene: 71819
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:61824559-61854078 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 33.50 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    862 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919069
 protein coding gene Chr9:61823187-61854078 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034916
 protein coding gene Chr9:61417869-61451101 (-)
A/J MGP_AJ_G0034896
 protein coding gene Chr9:59413904-59443056 (-)
AKR/J MGP_AKRJ_G0034826
 protein coding gene Chr9:60782352-60811265 (-)
BALB/cJ MGP_BALBcJ_G0034889
 protein coding gene Chr9:59131685-59161647 (-)
C3H/HeJ MGP_C3HHeJ_G0034599
 protein coding gene Chr9:61277573-61308890 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035408
 protein coding gene Chr9:63077143-63119372 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032319
 protein coding gene Chr9:59093593-59123076 (-)
CAST/EiJ MGP_CASTEiJ_G0033920
 protein coding gene Chr9:61401887-61433358 (-)
CBA/J MGP_CBAJ_G0034570
 protein coding gene Chr9:65268186-65297497 (-)
DBA/2J MGP_DBA2J_G0034729
 protein coding gene Chr9:59214521-59244409 (-)
FVB/NJ MGP_FVBNJ_G0034671
 protein coding gene Chr9:58497017-58527381 (-)
LP/J MGP_LPJ_G0034812
 protein coding gene Chr9:61711024-61741052 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034714
 protein coding gene Chr9:66685485-66717582 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035430
 protein coding gene Chr9:60856352-60885064 (-)
PWK/PhJ MGP_PWKPhJ_G0033624
 protein coding gene Chr9:59322172-59353099 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033457
 protein coding gene Chr9:61137243-61167474 (-)
WSB/EiJ MGP_WSBEiJ_G0034033
 protein coding gene Chr9:60760374-60792785 (-)



Homology
more
  • Human Ortholog
    KIF23, kinesin family member 23
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIF23, kinesin family member 23
  • Synonyms
    CDA3, CDAIII, CDAN3, CDAN3A, CHO1, KNSL5, MKLP-1, MKLP1
  • Links
    NCBI Gene ID: 9493
    neXtProt AC: NX_Q02241
    UniProt: Q02241

  • Chr Location
    15q23; chr15:69414246-69448427 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human KIF23 associations

Human Disease Mouse Models
      
IDs
 View 2 "NOT" models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    848
  • Tissues
    20
  • cDNA Data
    88
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71819 NCBI Gene Model | MGI Sequence Detail 29520 C57BL/6J ±  kb
transcript NM_001405055 RefSeq | MGI Sequence Detail 3406 C57BL/6  
polypeptide E9Q5G3 UniProt | EBI | MGI Sequence Detail 953 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000009302 kinesin-like protein KIF23
    (term hierarchy)
  • InterPro Domains
    IPR027640 Kinesin-like protein
    IPR032384 Kinesin-like protein Kif23, Arf6-interacting domain
    IPR038105 Kinesin-like protein Kif23, Arf6-interacting domain superfamily
    IPR001752 Kinesin motor domain
    IPR019821 Kinesin motor domain, conserved site
    IPR036961 Kinesin motor domain superfamily
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
  • GlyGen
    E9Q5G3 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 89
    cDNA 88
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143440
References
more
  • Summaries
    All 53
    Developmental Gene Expression 11
    Diseases 1
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:346372 Kolesova H, et al., Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure. Front Endocrinol (Lausanne). 2024;15:1344074
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory