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Slc17a9 Gene Detail
Summary
  • Symbol
    Slc17a9
  • Name
    solute carrier family 17, member 9
  • Synonyms
    1700019H03Rik, MGC:28538, Vnut
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919107
    NCBI Gene: 228993
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:180367056-180384073 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.28 cM, cytoband H4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    395 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919107
 protein coding gene Chr2:180363989-180384073 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027002
 protein coding gene Chr2:187263336-187286751 (+)
A/J MGP_AJ_G0026968
 protein coding gene Chr2:179569990-179589356 (+)
AKR/J MGP_AKRJ_G0026938
 protein coding gene Chr2:184954722-184973827 (+)
BALB/cJ MGP_BALBcJ_G0026977
 protein coding gene Chr2:180032295-180049918 (+)
C3H/HeJ MGP_C3HHeJ_G0026718
 protein coding gene Chr2:185302502-185322936 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027423
 protein coding gene Chr2:192669116-192690207 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024788
 protein coding gene Chr2:170261621-170277745 (+)
CAST/EiJ MGP_CASTEiJ_G0026177
 protein coding gene Chr2:183548254-183564944 (+)
CBA/J MGP_CBAJ_G0026695
 protein coding gene Chr2:199675667-199695490 (+)
DBA/2J MGP_DBA2J_G0026833
 protein coding gene Chr2:178665847-178684656 (+)
FVB/NJ MGP_FVBNJ_G0026799
 protein coding gene Chr2:177281558-177301421 (+)
LP/J MGP_LPJ_G0026934
 protein coding gene Chr2:187272959-187295993 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026818
 protein coding gene Chr2:202265863-202285728 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027482
 protein coding gene Chr2:184912166-184929849 (+)
PWK/PhJ MGP_PWKPhJ_G0025913
 protein coding gene Chr2:176179591-176197526 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025713
 protein coding gene Chr2:181408686-181430685 (+)
WSB/EiJ MGP_WSBEiJ_G0026249
 protein coding gene Chr2:185893222-185914671 (+)



Homology
more
  • Human Ortholog
    SLC17A9, solute carrier family 17 member 9
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC17A9, solute carrier family 17 member 9
  • Synonyms
    C20orf59, POROK8, VNUT
  • Links
    NCBI Gene ID: 63910
    neXtProt AC: NX_Q9BYT1
    UniProt: Q9BYT1

  • Chr Location
    20q13.33; chr20:62952707-62969585 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC17A9 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 3 alleles in 3 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout affects the neuroendocrine system, resulting in hypoglycemia, increased glucose tolerance and increased insulin sensitivity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    6
  • cDNA Data
    33
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000023393 Ensembl Gene Model | MGI Sequence Detail 17018 C57BL/6J ±  kb
    transcript ENSMUST00000094218 Ensembl | MGI Sequence Detail 2275 Not Applicable  
    polypeptide ENSMUSP00000091771 Ensembl | MGI Sequence Detail 447 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000014965 voltage-gated purine nucleotide uniporter SLC17A9
      (term hierarchy)
    • InterPro Domains
      IPR011701 Major facilitator superfamily
      IPR020846 Major facilitator superfamily domain
      IPR050382 Major Facilitator Superfamily Sodium/Anion Cotransporter
      IPR036259 MFS transporter superfamily
      IPR044777 Solute carrier family 17 member 9-like
      IPR005829 Sugar transporter, conserved site
    Molecular
    Reagents
    less
    • All nucleic 33
      cDNA 33

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2670971
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 21
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory