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Plpp5 Gene Detail
Summary
  • Symbol
    Plpp5
  • Name
    phospholipid phosphatase 5
  • Synonyms
    1810019D05Rik, 2310022A04Rik, Ppapdc1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919160
    NCBI Gene: 71910
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:26210064-26214914 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 14.17 cM, cytoband A3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    224 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919160
 protein coding gene Chr8:26210052-26214914 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033484
 protein coding gene Chr8:23786881-23791797 (+)
A/J MGP_AJ_G0033464
 protein coding gene Chr8:22922877-22927703 (+)
AKR/J MGP_AKRJ_G0033389
 protein coding gene Chr8:23679776-23686876 (+)
BALB/cJ MGP_BALBcJ_G0033460
 protein coding gene Chr8:23069311-23074137 (+)
C3H/HeJ MGP_C3HHeJ_G0033174
 protein coding gene Chr8:23892624-23897450 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033976
 protein coding gene Chr8:24752957-24757783 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030926
 protein coding gene Chr8:20193046-20197367 (+)
CAST/EiJ MGP_CASTEiJ_G0032500
 protein coding gene Chr8:23341580-23347443 (+)
CBA/J MGP_CBAJ_G0033149
 protein coding gene Chr8:25720872-25725698 (+)
DBA/2J MGP_DBA2J_G0033304
 protein coding gene Chr8:22893643-22898801 (+)
FVB/NJ MGP_FVBNJ_G0033248
 protein coding gene Chr8:22700160-22704986 (+)
LP/J MGP_LPJ_G0033393
 protein coding gene Chr8:23764805-23770320 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033291
 protein coding gene Chr8:25175614-25184512 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033995
 protein coding gene Chr8:23614287-23620501 (+)
PWK/PhJ MGP_PWKPhJ_G0032211
 protein coding gene Chr8:22535151-22540282 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032045
 protein coding gene Chr8:22984297-22989115 (+)
WSB/EiJ MGP_WSBEiJ_G0032616
 protein coding gene Chr8:23833761-23839466 (+)



Homology
more
  • Human Ortholog
    PLPP5, phospholipid phosphatase 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLPP5, phospholipid phosphatase 5
  • Synonyms
    DPPL1, HTPAP, PPAPDC1B
  • Links
    NCBI Gene ID: 84513
    neXtProt AC: NX_Q8NEB5
    UniProt: Q8NEB5

  • Chr Location
    8p11.23; chr8:38263130-38269243 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    5 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no significant alterations in the development, maturation and differentiation of B-lymphocytes or production of antibodies by antibody secreting cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    56
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031570 Ensembl Gene Model | MGI Sequence Detail 4851 C57BL/6J ±  kb
transcript ENSMUST00000068916 Ensembl | MGI Sequence Detail 1483 Not Applicable  
polypeptide ENSMUSP00000067035 Ensembl | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919256, MGI:2138539
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265892 Trezise S, et al., Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins. Int J Mol Sci. 2018 Jul 24;19(8):2161
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory