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Zfp654 Gene Detail
Summary
  • Symbol
    Zfp654
  • Name
    zinc finger protein 654
  • Synonyms
    1600021C16Rik, 1810008K20Rik, Gm5488
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919270
    NCBI Gene: 72020
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:64600710-64672015 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 37.10 cM, cytoband C1.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1326 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919270
 protein coding gene Chr16:64600710-64672300 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022941
 protein coding gene Chr16:64289675-64364492 (-)
A/J MGP_AJ_G0022909
 protein coding gene Chr16:61543288-61607022 (-)
AKR/J MGP_AKRJ_G0022879
 protein coding gene Chr16:63419987-63486383 (-)
BALB/cJ MGP_BALBcJ_G0022911
 protein coding gene Chr16:61749898-61818002 (-)
C3H/HeJ MGP_C3HHeJ_G0022673
 protein coding gene Chr16:63763145-63832420 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023359
 protein coding gene Chr16:66223260-66293254 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020862
 protein coding gene Chr16:60599306-60664197 (-)
CAST/EiJ MGP_CASTEiJ_G0022196
 protein coding gene Chr16:64013603-64081334 (-)
CBA/J MGP_CBAJ_G0022644
 protein coding gene Chr16:68971025-69048302 (-)
DBA/2J MGP_DBA2J_G0022776
 protein coding gene Chr16:61300032-61369309 (-)
FVB/NJ MGP_FVBNJ_G0022750
 protein coding gene Chr16:60919325-60991065 (-)
LP/J MGP_LPJ_G0022845
 protein coding gene Chr16:64091776-64163405 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022769
 protein coding gene Chr16:70206871-70299538 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023375
 protein coding gene Chr16:63562891-63633063 (-)
PWK/PhJ MGP_PWKPhJ_G0021939
 protein coding gene Chr16:61457952-61527058 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021768
 protein coding gene Chr16:63247731-63312099 (-)
WSB/EiJ MGP_WSBEiJ_G0022243
 protein coding gene Chr16:63620333-63688167 (-)



Homology
more
  • Human Ortholog
    ZNF654, zinc finger protein 654
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF654, zinc finger protein 654
  • Links
    NCBI Gene ID: 55279
    UniProt: Q8IZM8

  • Chr Location
    3p11.1; chr3:88059255-88144660 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    8
  • cDNA Data
    31
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047141 Ensembl Gene Model | MGI Sequence Detail 71306 C57BL/6J ±  kb
transcript ENSMUST00000207826 Ensembl | MGI Sequence Detail 6261 Not Applicable  
polypeptide ENSMUSP00000146656 Ensembl | MGI Sequence Detail 1112 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 31
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916343, MGI:3779491
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory