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Poglut2 Gene Detail
Summary
  • Symbol
    Poglut2
  • Name
    protein O-glucosyltransferase 2
  • Synonyms
    1810049A15Rik, 5730416C13Rik, EP58, Kdel1, Kdelc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919300
    NCBI Gene: 72050
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:44145706-44157968 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 23.54 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    416 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919300
 protein coding gene Chr1:44143060-44158844 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015987
 protein coding gene Chr1:43147157-43159407 (-)
A/J MGP_AJ_G0015971
 protein coding gene Chr1:41807695-41819949 (-)
AKR/J MGP_AKRJ_G0015926
 protein coding gene Chr1:42388117-42400371 (-)
BALB/cJ MGP_BALBcJ_G0015925
 protein coding gene Chr1:41492180-41504434 (-)
C3H/HeJ MGP_C3HHeJ_G0015758
 protein coding gene Chr1:42771493-42783746 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016378
 protein coding gene Chr1:44882081-44894333 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014100
 protein coding gene Chr1:38645572-38657820 (-)
CAST/EiJ MGP_CASTEiJ_G0015339
 protein coding gene Chr1:42795722-42807912 (-)
CBA/J MGP_CBAJ_G0015730
 protein coding gene Chr1:46189400-46201660 (-)
DBA/2J MGP_DBA2J_G0015831
 protein coding gene Chr1:41114065-41126319 (-)
FVB/NJ MGP_FVBNJ_G0015833
 protein coding gene Chr1:40615135-40627378 (-)
LP/J MGP_LPJ_G0015901
 protein coding gene Chr1:43465965-43478230 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015853
 protein coding gene Chr1:48161897-48174170 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016425
 protein coding gene Chr1:42608404-42620668 (-)
PWK/PhJ MGP_PWKPhJ_G0015122
 protein coding gene Chr1:40988184-41000642 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014904
 protein coding gene Chr1:42634224-42646365 (-)
WSB/EiJ MGP_WSBEiJ_G0015401
 protein coding gene Chr1:42653520-42665761 (-)



Homology
more
  • Human Ortholog
    POGLUT2, protein O-glucosyltransferase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POGLUT2, protein O-glucosyltransferase 2
  • Synonyms
    EP58, ERp58, KDEL1, KDELC1
  • Links
    NCBI Gene ID: 79070
    neXtProt AC: NX_Q6UW63
    UniProt: Q6UW63

  • Chr Location
    13q33.1; chr13:102784281-102799040 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotypes from multigenic genotypes
    9 phenotype references
Homozygous null mice are viable, fertile, and present at expected ratios.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    727
  • Tissues
    17
  • cDNA Data
    63
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026047 Ensembl Gene Model | MGI Sequence Detail 12263 C57BL/6J ±  kb
transcript ENSMUST00000065767 Ensembl | MGI Sequence Detail 2359 Not Applicable  
polypeptide ENSMUSP00000064500 Ensembl | MGI Sequence Detail 502 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 67
    cDNA 64
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917775, MGI:6285830
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:67334 Kimata Y, et al., Identification of a novel mammalian endoplasmic reticulum-resident KDEL protein using an EST database motif search. Gene. 2000 Dec 31;261(2):321-7
  • Latest
    J:350484 Neupane S, et al., Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues. J Biol Chem. 2024 Jun 4;300(7):107445
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory