Zbed3 MGI Mouse Gene Detail - MGI:1919364 - zinc finger, BED type containing 3

Symbol

Zbed3
Name

zinc finger, BED type containing 3
Synonyms

0610037K01Rik, 2610005H11Rik

Feature Type

protein coding gene
IDs

MGI:1919364
NCBI Gene: 72114
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr13:95460120-95474349 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 49.38 cM
Mapping Data

2 experiments

SNPs within 2kb

524 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919364	protein coding gene	Chr13:95460113-95474350 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020838	protein coding gene	Chr13:96782691-96795222 (+)
A/J	MGP_AJ_G0020792	protein coding gene	Chr13:93155376-93167978 (+)
AKR/J	MGP_AKRJ_G0020766	protein coding gene	Chr13:95996684-96010590 (+)
BALB/cJ	MGP_BALBcJ_G0020789	protein coding gene	Chr13:93835887-93849209 (+)
C3H/HeJ	MGP_C3HHeJ_G0020582	protein coding gene	Chr13:95698658-95711661 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021225	protein coding gene	Chr13:99725802-99738668 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018794	protein coding gene	Chr13:88991233-89003983 (+)
CAST/EiJ	MGP_CASTEiJ_G0020101	protein coding gene	Chr13:94993624-95007954 (+)
CBA/J	MGP_CBAJ_G0020541	protein coding gene	Chr13:103681520-103696653 (+)
DBA/2J	MGP_DBA2J_G0020666	protein coding gene	Chr13:92940412-92953012 (+)
FVB/NJ	MGP_FVBNJ_G0020647	protein coding gene	Chr13:91726519-91739005 (+)
LP/J	MGP_LPJ_G0020741	protein coding gene	Chr13:96902847-96915779 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020675	protein coding gene	Chr13:104129659-104142924 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021265	protein coding gene	Chr13:95400727-95414827 (+)
PWK/PhJ	MGP_PWKPhJ_G0019853	protein coding gene	Chr13:91700634-91713922 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019677	protein coding gene	Chr13:91689898-91702548 (+)
WSB/EiJ	MGP_WSBEiJ_G0020158	protein coding gene	Chr13:95901367-95913968 (+)

Human Ortholog

ZBED3, zinc finger BED-type containing 3

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZBED3, zinc finger BED-type containing 3
Links

HGNC:20711

NCBI Gene ID: 84327

neXtProt AC: NX_Q96IU2

UniProt: Q96IU2
Chr Location

5q13.3; chr5:77072072-77087285 (-) GRCh38

MGI Vertebrate Homology

Zbed3 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: ZBED3
Gene Tree

Zbed3

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Phenotype Summary

6 phenotypes from 2 alleles in 2 genetic backgrounds
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Endonuclease-mediated

2
Gene trapped

5
Targeted

3
Incidental Mutations

APF
Find Mice (IMSR)

16 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Homozygous knockout has a maternal effect in reduced litter size owing to cytoskeletal abnormalities affecting early zygote development.

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All GO Annotations

25
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

732
Tissues

8
cDNA Data

16
Literature Summary

7

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

57
RefSeq

8
UniProt

4
CCDS

CCDS26696.1

Ensembl

ENSMUSG00000041995 (Evidence)
NCBI Gene

72114

			Length	Strain/Species	Flank
genomic	ENSMUSG00000041995	Ensembl Gene Model \| MGI Sequence Detail	14230	C57BL/6J	± kb
transcript	ENSMUST00000221807	Ensembl \| MGI Sequence Detail	1945	Not Applicable
polypeptide	ENSMUSP00000152153	Ensembl \| MGI Sequence Detail	228	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000029882 zinc finger BED domain-containing protein 3

(term hierarchy)
InterPro Domains

IPR043471 Zinc finger BED domain-containing protein 2/3

IPR036236 Zinc finger C2H2 superfamily

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All nucleic 17

cDNA 17

Microarray probesets 4

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MGI:1915634, MGI:2145348, MGI:2145367

Summaries

All 36

Developmental Gene Expression 7

Gene Ontology 7

Phenotypes 8
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:344223 Zhang W, et al., NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance. Cell Rep. 2023 Dec 26;42(12):113531

TSS for Zbed3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr120712	Chr13:95460110-95460114 (+)	-8 bp
Tssr120713	Chr13:95461322-95461382 (+)	1,232 bp
Tssr120714	Chr13:95461650-95461667 (+)	1,539 bp
Tssr120715	Chr13:95461677-95461697 (+)	1,567 bp
Tssr120716	Chr13:95461703-95461737 (+)	1,600 bp
Tssr120717	Chr13:95461766-95461808 (+)	1,667 bp
Tssr120718	Chr13:95462384-95462387 (+)	2,266 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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