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Cyp2c65 Gene Detail
Summary
  • Symbol
    Cyp2c65
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 65
  • Synonyms
    2210009K14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919553
    NCBI Gene: 72303
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:39049459-39082388 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 33.70 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    854 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919553
 protein coding gene Chr19:39049450-39082392 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025098
 protein coding gene Chr19:38188056-38218555 (+)
A/J MGP_AJ_G0025074
 protein coding gene Chr19:36328733-36360201 (+)
AKR/J MGP_AKRJ_G0025042
 protein coding gene Chr19:37536541-37570516 (+)
BALB/cJ MGP_BALBcJ_G0025072
 protein coding gene Chr19:36417408-36453209 (+)
C3H/HeJ MGP_C3HHeJ_G0024831
 protein coding gene Chr19:37633843-37670586 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025513
 protein coding gene Chr19:39235768-39271708 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022932
 protein coding gene Chr19:35627639-35658527 (+)
CAST/EiJ MGP_CASTEiJ_G0024298
 protein coding gene Chr19:37493372-37562174 (+)
CBA/J MGP_CBAJ_G0024808
 protein coding gene Chr19:41150404-41179462 (+)
DBA/2J MGP_DBA2J_G0024940
 protein coding gene Chr19:36154191-36186422 (+)
FVB/NJ MGP_FVBNJ_G0024901
 protein coding gene Chr19:35978704-36009841 (+)
LP/J MGP_LPJ_G0025026
 protein coding gene Chr19:38258242-38305317 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024932
 protein coding gene Chr19:40821552-40852503 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025571
 protein coding gene Chr19:37652703-37685619 (+)
PWK/PhJ MGP_PWKPhJ_G0024050
 protein coding gene Chr19:36023929-36063130 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023850
 protein coding gene Chr19:36469912-36731419 (+)
WSB/EiJ MGP_WSBEiJ_G0024366
 protein coding gene Chr19:37746250-37781008 (+)



Homology
more
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Synonyms
    CPC8, CYP2C8DM, CYPIIC8, MP-12/MP-20
  • Links
    NCBI Gene ID: 1558
    neXtProt AC: NX_P10632
    UniProt: P10632

  • Chr Location
    10q23.33; chr10:95036772-95069497 (-)  GRCh38
  • Human Ortholog
    CYP2C9, cytochrome P450 family 2 subfamily C member 9
  • Synonyms
    CPC9, CYP2C, CYP2C10, CYPIIC9, P450-2C9, P450IIC9
  • Links
    NCBI Gene ID: 1559
    neXtProt AC: NX_P11712
    UniProt: P11712

  • Chr Location
    10q23.33; chr10:94938658-94990091 (+)  GRCh38
Human Diseases
more
  • Diseases
    21 with human CYP2C19,CYP2C8,CYP2C9 associations

Human Disease Mouse Models
      
IDs
IDs
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Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067231 Ensembl Gene Model | MGI Sequence Detail 32930 C57BL/6J ±  kb
transcript ENSMUST00000087236 Ensembl | MGI Sequence Detail 1928 Not Applicable  
polypeptide ENSMUSP00000084489 Ensembl | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:341617 Zhang J, et al., CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 Jul;37(7):e23009
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory