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Obi1 Gene Detail
Summary
  • Symbol
    Obi1
  • Name
    ORC ubiquitin ligase 1
  • Synonyms
    2610206B13Rik, 2810449K13Rik, MGC:35679, Rnf219
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919736
    NCBI Gene: 72486
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:104714972-104760081 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 54.24 cM, cytoband E2.2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1343 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919736
protein coding gene Chr14:104714970-104760148 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021635
protein coding gene Chr14:101039071-101085399 (-)
A/J MGP_AJ_G0021593
protein coding gene Chr14:97672003-97717831 (-)
AKR/J MGP_AKRJ_G0021569
protein coding gene Chr14:100610689-100657379 (-)
BALB/cJ MGP_BALBcJ_G0021599
protein coding gene Chr14:98032872-98078484 (-)
C3H/HeJ MGP_C3HHeJ_G0021377
protein coding gene Chr14:100513277-100558990 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022039
protein coding gene Chr14:105118867-105166318 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019579
protein coding gene Chr14:94497823-94544779 (-)
CAST/EiJ MGP_CASTEiJ_G0020894
protein coding gene Chr14:97856851-97903406 (-)
CBA/J MGP_CBAJ_G0021345
protein coding gene Chr14:108884801-108929828 (-)
DBA/2J MGP_DBA2J_G0021469
protein coding gene Chr14:97183845-97228958 (-)
FVB/NJ MGP_FVBNJ_G0021446
protein coding gene Chr14:96145332-96191138 (-)
LP/J MGP_LPJ_G0021537
protein coding gene Chr14:101849140-101894256 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021473
protein coding gene Chr14:111716907-111762925 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022062
protein coding gene Chr14:100136092-100182130 (-)
PWK/PhJ MGP_PWKPhJ_G0020637
protein coding gene Chr14:94151801-94197667 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020475
protein coding gene Chr14:96165151-96212488 (-)
WSB/EiJ MGP_WSBEiJ_G0020947
protein coding gene Chr14:100785699-100831208 (-)



Homology
more
  • Human Ortholog
    OBI1, ORC ubiquitin ligase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OBI1, ORC ubiquitin ligase 1
  • Synonyms
    C13orf7, RNF219
  • Links
    NCBI Gene ID: 79596
    neXtProt AC: NX_Q5W0B1
    UniProt: Q5W0B1

  • Chr Location
    13q31.1; chr13:78614289-78659155 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022120 Ensembl Gene Model | MGI Sequence Detail 45110 C57BL/6J ±  kb
transcript ENSMUST00000022716 Ensembl | MGI Sequence Detail 3420 Not Applicable  
polypeptide ENSMUSP00000022716 Ensembl | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 43
    cDNA 43

    Microarray probesets 7
Other
Accession IDs
less
MGI:1914483, MGI:2145655, MGI:6393865
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:204486 Zheng S, et al., A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. Genome Res. 2013 Jun;23(6):998-1007

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory