Bltp2 MGI Mouse Gene Detail - MGI:1919753 - bridge-like lipid transfer protein family member 2

Symbol

Bltp2
Name

bridge-like lipid transfer protein family member 2
Synonyms

2610507B11Rik, mKIAA0100

Feature Type

protein coding gene
IDs

MGI:1919753
NCBI Gene: 72503
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr11:78152578-78181449 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 46.74 cM, cytoband B5
Mapping Data

5 experiments

SNPs within 2kb

496 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919753	protein coding gene	Chr11:78152476-78181451 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018772	protein coding gene	Chr11:79253072-79283835 (+)
A/J	MGP_AJ_G0018738	protein coding gene	Chr11:76224296-76253266 (+)
AKR/J	MGP_AKRJ_G0018708	protein coding gene	Chr11:78528059-78556884 (+)
BALB/cJ	MGP_BALBcJ_G0018712	protein coding gene	Chr11:76632176-76661680 (+)
C3H/HeJ	MGP_C3HHeJ_G0018525	protein coding gene	Chr11:78568332-78598238 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019163	protein coding gene	Chr11:81725244-81756963 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016798	protein coding gene	Chr11:73196457-73225672 (+)
CAST/EiJ	MGP_CASTEiJ_G0018079	protein coding gene	Chr11:79012334-79046148 (+)
CBA/J	MGP_CBAJ_G0018495	protein coding gene	Chr11:85297139-85335174 (+)
DBA/2J	MGP_DBA2J_G0018604	protein coding gene	Chr11:75802923-75832094 (+)
FVB/NJ	MGP_FVBNJ_G0018594	protein coding gene	Chr11:75391746-75421081 (+)
LP/J	MGP_LPJ_G0018675	protein coding gene	Chr11:79788719-79819831 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018620	protein coding gene	Chr11:85707683-85737125 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019203	protein coding gene	Chr11:78771369-78802684 (+)
PWK/PhJ	MGP_PWKPhJ_G0017850	protein coding gene	Chr11:76590111-76619902 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017641	protein coding gene	Chr11:78382976-78412205 (+)
WSB/EiJ	MGP_WSBEiJ_G0018132	protein coding gene	Chr11:78587313-78618428 (+)

Human Ortholog

BLTP2, bridge-like lipid transfer protein family member 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

BLTP2, bridge-like lipid transfer protein family member 2
Synonyms

BCOX, BCOX1, CT101, FMP27, Hob, KIAA0100
Links

HGNC:28960

NCBI Gene ID: 9703

neXtProt AC: NX_Q14667

UniProt: Q14667
Chr Location

17q11.2; chr17:28614440-28645454 (-) GRCh38

MGI Vertebrate Homology

Bltp2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: BLTP2
Gene Tree

Bltp2

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
17 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

4
Targeted

3
Genomic Mutations

2 involving Bltp2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

79 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

5
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

859
Tissues

21
cDNA Data

360
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

59
RefSeq

10
UniProt

3
CCDS

CCDS25097.1

Ensembl

ENSMUSG00000010277 (Evidence)
NCBI Gene

72503

			Length	Strain/Species	Flank
genomic	ENSMUSG00000010277	Ensembl Gene Model \| MGI Sequence Detail	28872	C57BL/6J	± kb
transcript	ENSMUST00000010421	Ensembl \| MGI Sequence Detail	7443	Not Applicable
polypeptide	ENSMUSP00000010421	Ensembl \| MGI Sequence Detail	2234	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000059780 bridge-like lipid transfer protein family member 2

(term hierarchy)
InterPro Domains

IPR019443 BLTP2/FMP27/Hobbit, C-terminal

IPR048872 BLTP2, sixth RBG module

IPR019441 FMP27/BLTP2/Hobbit, GFWDK motif-containing RBG unit

IPR019439 FMP27/BLTP2, N-terminal

IPR045167 Hobbit
GlyGen

Q5SYL3 4 sites, 4 N-linked glycans (4 sites)

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All nucleic 367

Genomic 4

cDNA 361

Primer pair 2

Microarray probesets 4

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MGD-MRK-35276, MGD-MRK-35277, MGI:106816, MGI:106817, MGI:2144415, MGI:7284368

Summaries

All 44

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 17
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Bltp2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr103256	Chr11:78152543-78152629 (+)	8 bp
Tssr103257	Chr11:78153303-78153306 (+)	727 bp
Tssr103258	Chr11:78153602-78153626 (+)	1,036 bp
Tssr103259	Chr11:78154223-78154244 (+)	1,656 bp
Tssr103260	Chr11:78157208-78157222 (+)	4,637 bp
Tssr103261	Chr11:78157761-78157778 (+)	5,192 bp
Tssr3587	Chr11:78158918-78158962 (+)	6,362 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24