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Dzip1l Gene Detail
Summary
  • Symbol
    Dzip1l
  • Name
    DAZ interacting protein 1-like
  • Synonyms
    2610524A10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919757
    NCBI Gene: 72507
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:99511549-99551309 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 51.93 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1367 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919757
 protein coding gene Chr9:99511448-99552128 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035173
 protein coding gene Chr9:101007794-101052108 (+)
A/J MGP_AJ_G0035154
 protein coding gene Chr9:97446279-97486723 (+)
AKR/J MGP_AKRJ_G0035086
 protein coding gene Chr9:99813315-99855196 (+)
BALB/cJ MGP_BALBcJ_G0035147
 protein coding gene Chr9:97133324-97177197 (+)
C3H/HeJ MGP_C3HHeJ_G0034857
 protein coding gene Chr9:100235319-100277437 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035667
 protein coding gene Chr9:103899745-103945841 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032566
 protein coding gene Chr9:95167165-95206954 (+)
CAST/EiJ MGP_CASTEiJ_G0034168
 protein coding gene Chr9:100039951-100083952 (+)
CBA/J MGP_CBAJ_G0034825
 protein coding gene Chr9:107457153-107506352 (+)
DBA/2J MGP_DBA2J_G0034987
 protein coding gene Chr9:96956462-96996770 (+)
FVB/NJ MGP_FVBNJ_G0034935
 protein coding gene Chr9:95773414-95813274 (+)
LP/J MGP_LPJ_G0035063
 protein coding gene Chr9:101255758-101301276 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034974
 protein coding gene Chr9:109372305-109416912 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035689
 protein coding gene Chr9:100066487-100108975 (+)
PWK/PhJ MGP_PWKPhJ_G0033875
 protein coding gene Chr9:97170560-97211802 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033710
 protein coding gene Chr9:100122493-100174114 (+)
WSB/EiJ MGP_WSBEiJ_G0034288
 protein coding gene Chr9:99949394-99992773 (+)



Homology
more
  • Human Ortholog
    DZIP1L, DAZ interacting zinc finger protein 1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DZIP1L, DAZ interacting zinc finger protein 1 like
  • Synonyms
    DZIP2, PKD5
  • Links
    NCBI Gene ID: 199221
    neXtProt AC: NX_Q8IYY4
    UniProt: Q8IYY4

  • Chr Location
    3q22.3; chr3:138061990-138115818 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Dzip1l mouse models; 1 with human DZIP1L associations

Human Disease Mouse Models
      
IDs
 View 2 models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotypes from 2 alleles in 3 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation exhibit early onset, progressive cystic kidney disease, polydactyly, facial clefting, eye defects, and prenatal lethality. Craniofacial defects and lethality are ameliorated in mice with an outbred genetic background.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    3
  • cDNA Data
    28
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037784 Ensembl Gene Model | MGI Sequence Detail 39761 C57BL/6J ±  kb
    transcript ENSMUST00000112885 Ensembl | MGI Sequence Detail 4350 Not Applicable  
    polypeptide ENSMUSP00000108506 Ensembl | MGI Sequence Detail 774 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 28
      Other 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2143112
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory