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Atxn7l2 Gene Detail
Summary
  • Symbol
    Atxn7l2
  • Name
    ataxin 7-like 2
  • Synonyms
    2610528J18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919772
    NCBI Gene: 72522
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:108109538-108117843 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 46.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919772
 protein coding gene Chr3:108109538-108118250 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027770
 protein coding gene Chr3:109741342-109750054 (-)
A/J MGP_AJ_G0027730
 protein coding gene Chr3:106262661-106271373 (-)
AKR/J MGP_AKRJ_G0027695
 protein coding gene Chr3:108849119-108857831 (-)
BALB/cJ MGP_BALBcJ_G0027742
 protein coding gene Chr3:105963833-105972545 (-)
C3H/HeJ MGP_C3HHeJ_G0027472
 protein coding gene Chr3:109192512-109201224 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028186
 protein coding gene Chr3:113846096-113854808 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025524
 protein coding gene Chr3:102414083-102422800 (-)
CAST/EiJ MGP_CASTEiJ_G0026928
 protein coding gene Chr3:108577884-108586594 (-)
CBA/J MGP_CBAJ_G0027447
 protein coding gene Chr3:117709488-117718200 (-)
DBA/2J MGP_DBA2J_G0027589
 protein coding gene Chr3:105444708-105453420 (-)
FVB/NJ MGP_FVBNJ_G0027557
 protein coding gene Chr3:103332153-103340932 (-)
LP/J MGP_LPJ_G0027696
 protein coding gene Chr3:111159253-111167965 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027587
 protein coding gene Chr3:123776261-123786092 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028241
 protein coding gene Chr3:108447835-108456545 (-)
PWK/PhJ MGP_PWKPhJ_G0026654
 protein coding gene Chr3:105194471-105203298 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026474
 protein coding gene Chr3:106583756-106592463 (-)
WSB/EiJ MGP_WSBEiJ_G0027008
 protein coding gene Chr3:108977148-108985880 (-)



Homology
more
  • Human Ortholog
    ATXN7L2, ataxin 7 like 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATXN7L2, ataxin 7 like 2
  • Links
    NCBI Gene ID: 127002
    neXtProt AC: NX_Q5T6C5
    UniProt: Q5T6C5

  • Chr Location
    1p13.3; chr1:109483479-109492804 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    37
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72522 NCBI Gene Model | MGI Sequence Detail 8306 C57BL/6J ±  kb
    transcript NM_175183 RefSeq | MGI Sequence Detail 2637 C57BL/6  
    polypeptide NP_001276474 RefSeq | MGI Sequence Detail 754 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • InterPro Domains
      IPR052237 Ataxin-7-like transcription regulator
      IPR013243 SCA7 domain
    Molecular
    Reagents
    less
    • All nucleic 37
      cDNA 37

      Microarray probesets 3
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 1
      Diseases 1
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:347599 Raja R, et al., Insertion of a neomycin selection cassette in the Amigo1 locus alters gene expression in the olfactory epithelium leading to region-specific defects in olfactory receptor neuron development. Genesis. 2024 Apr;62(2):e23594
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory