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Pcbd2 Gene Detail
Summary
  • Symbol
    Pcbd2
  • Name
    pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
  • Synonyms
    2700061N24Rik, Dcoh2, Dcohm
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919812
    NCBI Gene: 72562
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:55875181-55924643 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 30.06 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1335 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919812
 protein coding gene Chr13:55874957-55924643 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020610
 protein coding gene Chr13:55231912-55285449 (+)
A/J MGP_AJ_G0020564
 protein coding gene Chr13:53190519-53239524 (+)
AKR/J MGP_AKRJ_G0020542
 protein coding gene Chr13:54769583-54824409 (+)
BALB/cJ MGP_BALBcJ_G0020560
 protein coding gene Chr13:53419556-53470973 (+)
C3H/HeJ MGP_C3HHeJ_G0020359
 protein coding gene Chr13:54569731-54625479 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020994
 protein coding gene Chr13:56887672-56947336 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018576
 protein coding gene Chr13:51123621-51171787 (+)
CAST/EiJ MGP_CASTEiJ_G0019873
 protein coding gene Chr13:54682384-54734489 (+)
CBA/J MGP_CBAJ_G0020319
 protein coding gene Chr13:59084985-59142234 (+)
DBA/2J MGP_DBA2J_G0020442
 protein coding gene Chr13:52736927-52789519 (+)
FVB/NJ MGP_FVBNJ_G0020421
 protein coding gene Chr13:52205301-52255933 (+)
LP/J MGP_LPJ_G0020518
 protein coding gene Chr13:55481970-55538951 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020450
 protein coding gene Chr13:58537204-58591811 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021037
 protein coding gene Chr13:54343271-54396761 (+)
PWK/PhJ MGP_PWKPhJ_G0019629
 protein coding gene Chr13:52765215-52815720 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019456
 protein coding gene Chr13:53265349-53317945 (+)
WSB/EiJ MGP_WSBEiJ_G0019935
 protein coding gene Chr13:54711193-54762949 (+)



Homology
more
  • Human Ortholog
    PCBD2, pterin-4 alpha-carbinolamine dehydratase 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCBD2, pterin-4 alpha-carbinolamine dehydratase 2
  • Synonyms
    DCOH2, DCOHM, PHS2
  • Links
    NCBI Gene ID: 84105
    neXtProt AC: NX_Q9H0N5
    UniProt: Q9H0N5

  • Chr Location
    5q31.1; chr5:134905120-135007959 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    719
  • Tissues
    13
  • cDNA Data
    29
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021496 Ensembl Gene Model | MGI Sequence Detail 49463 C57BL/6J ±  kb
transcript ENSMUST00000021958 Ensembl | MGI Sequence Detail 544 Not Applicable  
polypeptide ENSMUSP00000021958 Ensembl | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:271427 Thompson AC, et al., A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates. Elife. 2018 Nov 30;7:e38555
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory