Car10 Gene Detail

Summary

• Symbol
  Car10
• Name
  carbonic anhydrase 10
• Synonyms
  2700029L05Rik, CA-RP X

• Feature Type
  protein coding gene
• IDs
  MGI:1919855
  NCBI Gene: 72605
• Alliance
  gene page
• Transcription Start Sites
  13 TSS

Location &
Maps

• Sequence Map
  Chr11:92988854-93492575 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 58.43 cM, cytoband C
• Mapping Data
  4 experiments

Strain
Comparison

• SNPs within 2kb
  15134 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919855	protein coding gene	Chr11:92988807-93492577 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018943	protein coding gene	Chr11:95076103-95617703 (+)
A/J	MGP_AJ_G0018911	protein coding gene	Chr11:91324192-91834635 (+)
AKR/J	MGP_AKRJ_G0018881	protein coding gene	Chr11:94154125-94682529 (+)
BALB/cJ	MGP_BALBcJ_G0018884	protein coding gene	Chr11:91750483-92265402 (+)
C3H/HeJ	MGP_C3HHeJ_G0018698	protein coding gene	Chr11:94240913-94775158 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019336	protein coding gene	Chr11:98078849-98618981 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016967	protein coding gene	Chr11:88837209-89339160 (+)
CAST/EiJ	MGP_CASTEiJ_G0018253	protein coding gene	Chr11:94908609-95445667 (+)
CBA/J	MGP_CBAJ_G0018669	protein coding gene	Chr11:102137204-102718456 (+)
DBA/2J	MGP_DBA2J_G0018777	protein coding gene	Chr11:90892049-91395366 (+)
FVB/NJ	MGP_FVBNJ_G0018766	protein coding gene	Chr11:90326833-90823385 (+)
LP/J	MGP_LPJ_G0018847	protein coding gene	Chr11:95649773-96161015 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018793	protein coding gene	Chr11:102227790-102777220 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019376	protein coding gene	Chr11:94351097-94890704 (+)
PWK/PhJ	MGP_PWKPhJ_G0018023	protein coding gene	Chr11:91797404-92315728 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017813	protein coding gene	Chr11:94035829-94581397 (+)
WSB/EiJ	MGP_WSBEiJ_G0018302	protein coding gene	Chr11:94218815-94771114 (+)

Homology

• Human Ortholog
  CA10, carbonic anhydrase 10

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CA10, carbonic anhydrase 10
  
• Synonyms
  CA-RPX, CARPX, HUCEP-15
• Links
  HGNC:1369

  NCBI Gene ID: 56934

  neXtProt AC: NX_Q9NS85

  UniProt: Q9NS85

  
  
• Chr Location
  17q21.33-q22

---

• MGI Vertebrate Homology
  Car10 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CA10
• Gene Tree
  Car10
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  13 phenotype references
  

• All Mutations and Alleles
  12
• Endonuclease-mediated
  3
• Gene trapped
  5
• Targeted
  4
• Genomic Mutations
  3 involving Car10
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  17 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  2

Expression

• Assay Results
  880
• Tissues
  133
• cDNA Data
  14
• Literature Summary
  9

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  GEISHA CA10
  Xenbase ca10

Sequences &
Gene Models

• All Sequences
  65
• RefSeq
  10
• UniProt
  8
• CCDS
  CCDS25244.1

• Ensembl
  ENSMUSG00000056158 (Evidence)
• NCBI Gene
  72605

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000056158	Ensembl Gene Model | MGI Sequence Detail	503722	C57BL/6J
transcript	ENSMUST00000107863	Ensembl | MGI Sequence Detail	3334	Not Applicable
polypeptide	ENSMUSP00000103495	Ensembl | MGI Sequence Detail	328	Not Applicable

Protein
Information

• UniProt
  8 Sequences
• Protein Ontology
  PR:000004913 carbonic anhydrase-related protein 10
  (term hierarchy)
• InterPro Domains
  IPR001148 Alpha carbonic anhydrase domain
  IPR036398 Alpha carbonic anhydrase domain superfamily
  IPR023561 Carbonic anhydrase, alpha-class
  IPR041878 Carbonic anhydrase-related protein X/XI
• GlyGen
  P61215 4 sites, 6 N-linked glycans (3 sites), 1 O-linked glycan (1 site)

Molecular
Reagents

• All nucleic 17

  cDNA 14

  Primer pair 3

  
  

  Microarray probesets 5

Other
Accession IDs

MGI:2144598

References

• Summaries
  All 47

  Developmental Gene Expression 9

  Diseases 1

  Gene Ontology 2

  Phenotypes 13
• Earliest
  J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
• Latest
  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Car10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr104133	Chr11:92988863-92988882 (+)	19 bp
Tssr104134	Chr11:92989183-92989223 (+)	349 bp
Tssr104135	Chr11:92989231-92989263 (+)	393 bp
Tssr104136	Chr11:92990046-92990056 (+)	1,197 bp
Tssr104137	Chr11:92990066-92990075 (+)	1,217 bp
Tssr104138	Chr11:92990110-92990157 (+)	1,280 bp
Tssr104139	Chr11:92990491-92990502 (+)	1,643 bp
Tssr104140	Chr11:92991015-92991027 (+)	2,167 bp
Tssr104141	Chr11:93211108-93211111 (+)	222,256 bp
Tssr104145	Chr11:93312251-93312256 (+)	323,400 bp
Tssr104146	Chr11:93459642-93459645 (+)	470,790 bp
Tssr104147	Chr11:93488009-93488023 (+)	499,162 bp
Tssr104148	Chr11:93491312-93491343 (+)	502,474 bp