Yju2 MGI Mouse Gene Detail - MGI:1920136

Symbol

Yju2
Name

YJU2 splicing factor
Synonyms

2900016D05Rik, Ccdc94

Feature Type

protein coding gene
IDs

MGI:1920136
NCBI Gene: 72886
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr17:56266187-56274951 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 17, 29.08 cM
Mapping Data

2 experiments

SNPs within 2kb

289 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920136	protein coding gene	Chr17:56266099-56275285 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0023903	protein coding gene	Chr17:57581744-57590499 (+)
A/J	MGP_AJ_G0023863	protein coding gene	Chr17:56030394-56039130 (+)
AKR/J	MGP_AKRJ_G0023830	protein coding gene	Chr17:56706506-56719235 (+)
BALB/cJ	MGP_BALBcJ_G0023864	protein coding gene	Chr17:55864647-55873405 (+)
C3H/HeJ	MGP_C3HHeJ_G0023627	protein coding gene	Chr17:57421331-57430097 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024308	protein coding gene	Chr17:59864935-59873661 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0021755	protein coding gene	Chr17:52548582-52557689 (+)
CAST/EiJ	MGP_CASTEiJ_G0023110	protein coding gene	Chr17:57728541-57737235 (+)
CBA/J	MGP_CBAJ_G0023604	protein coding gene	Chr17:62157454-62166057 (+)
DBA/2J	MGP_DBA2J_G0023732	protein coding gene	Chr17:54764811-54773562 (+)
FVB/NJ	MGP_FVBNJ_G0023698	protein coding gene	Chr17:54280428-54290050 (+)
LP/J	MGP_LPJ_G0023812	protein coding gene	Chr17:58304275-58313026 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0023725	protein coding gene	Chr17:61725936-61737535 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024353	protein coding gene	Chr17:57087671-57099860 (+)
PWK/PhJ	MGP_PWKPhJ_G0022855	protein coding gene	Chr17:54106155-54115216 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0022667	protein coding gene	Chr17:53850581-53859372 (+)
WSB/EiJ	MGP_WSBEiJ_G0023174	protein coding gene	Chr17:57700816-57709627 (+)

Human Ortholog

YJU2, YJU2 splicing factor homolog

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

YJU2, YJU2 splicing factor homolog
Synonyms

CCDC94
Links

HGNC:25518

NCBI Gene ID: 55702

neXtProt AC: NX_Q9BW85

UniProt: Q9BW85
Chr Location

19p13.3; chr19:4247080-4269088 (+) GRCh38

MGI Vertebrate Homology

Yju2 stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: YJU2
Gene Tree

Yju2

less

Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

12
Endonuclease-mediated

1
Gene trapped

8
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

19 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

less

All GO Annotations

7
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

763
Tissues

33
cDNA Data

31
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase yju2

ZFIN yju2

less

All Sequences

35
RefSeq

2
UniProt

2
CCDS

CCDS37660.1

Ensembl

ENSMUSG00000003208 (Evidence)
NCBI Gene

72886

			Length	Strain/Species	Flank
genomic	72886	NCBI Gene Model \| MGI Sequence Detail	8765	C57BL/6J	± kb
transcript	NM_028381	RefSeq \| MGI Sequence Detail	1324	FVB/N
polypeptide	Q9D6J3	UniProt \| EBI \| MGI Sequence Detail	314	Not Applicable

less

UniProt

2 Sequences
Protein Ontology

PR:000029344 splicing factor YJU2

(term hierarchy)
InterPro Domains

IPR007590 Saf4/Yju2 protein

IPR043701 Splicing factor Yju2

less

All nucleic 31

cDNA 31

Microarray probesets 2

less

MGI:2146841, MGI:6156404

Summaries

All 36

Developmental Gene Expression 2

Gene Ontology 5

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Yju2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr145259	Chr17:56266125-56266140 (+)	-54 bp
Tssr145260	Chr17:56266146-56266182 (+)	-23 bp
Tssr145261	Chr17:56266765-56266784 (+)	588 bp
Tssr145262	Chr17:56268597-56268610 (+)	2,417 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24