About   Help   FAQ
Lrrc47 Gene Detail
Summary
  • Symbol
    Lrrc47
  • Name
    leucine rich repeat containing 47
  • Synonyms
    2900010D03Rik, mKIAA1185
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920196
    NCBI Gene: 72946
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:154096260-154105969 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 83.79 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    316 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920196
 protein coding gene Chr4:154096188-154105970 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029188
 protein coding gene Chr4:158244226-158255804 (+)
A/J MGP_AJ_G0029153
 protein coding gene Chr4:151614467-151624260 (+)
AKR/J MGP_AKRJ_G0029101
 protein coding gene Chr4:155746335-155756097 (+)
BALB/cJ MGP_BALBcJ_G0029169
 protein coding gene Chr4:152081967-152091771 (+)
C3H/HeJ MGP_C3HHeJ_G0028890
 protein coding gene Chr4:156281432-156292354 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029618
 protein coding gene Chr4:163910272-163921510 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026864
 protein coding gene Chr4:143916148-143926117 (+)
CAST/EiJ MGP_CASTEiJ_G0028303
 protein coding gene Chr4:153680283-153690670 (+)
CBA/J MGP_CBAJ_G0028852
 protein coding gene Chr4:168835768-168845541 (+)
DBA/2J MGP_DBA2J_G0029001
 protein coding gene Chr4:151640278-151650334 (+)
FVB/NJ MGP_FVBNJ_G0028965
 protein coding gene Chr4:150840085-150850277 (+)
LP/J MGP_LPJ_G0029091
 protein coding gene Chr4:158160308-158171440 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028992
 protein coding gene Chr4:171754499-171765301 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029650
 protein coding gene Chr4:156315326-156326000 (+)
PWK/PhJ MGP_PWKPhJ_G0028023
 protein coding gene Chr4:147716112-147726518 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027857
 protein coding gene Chr4:150602234-150612723 (+)
WSB/EiJ MGP_WSBEiJ_G0028383
 protein coding gene Chr4:156479869-156489608 (+)



Homology
more
  • Human Ortholog
    LRRC47, leucine rich repeat containing 47
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC47, leucine rich repeat containing 47
  • Links
    NCBI Gene ID: 57470
    neXtProt AC: NX_Q8N1G4
    UniProt: Q8N1G4

  • Chr Location
    1p36.32; chr1:3778559-3796498 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    749
  • Tissues
    29
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72946 NCBI Gene Model | MGI Sequence Detail 9710 C57BL/6J ±  kb
transcript NM_201226 RefSeq | MGI Sequence Detail 3395 Not Specified  
polypeptide Q505F5 UniProt | EBI | MGI Sequence Detail 581 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000030712 leucine-rich repeat-containing protein 47
    (term hierarchy)
  • InterPro Domains
    IPR005146 B3/B4 tRNA-binding domain
    IPR001611 Leucine-rich repeat
    IPR025875 Leucine rich repeat 4
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
    IPR045060 Phenylalanine-tRNA ligase, class IIc, beta subunit
    IPR020825 Phenylalanyl-tRNA synthetase-like, B3/B4
  • GlyGen
    Q505F5 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140182
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:196071 van der Weyden L, et al., Cancer of mice and men: old twists and new tails. J Pathol. 2013 May;230(1):4-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory