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Ppp1r16a Gene Detail
Summary
  • Symbol
    Ppp1r16a
  • Name
    protein phosphatase 1, regulatory subunit 16A
  • Synonyms
    2900084E10Rik, Mypt3, R75527
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920312
    NCBI Gene: 73062
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76555843-76579119 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    509 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920312
protein coding gene Chr15:76555815-76579119 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022006
protein coding gene Chr15:76766437-76797006 (+)
A/J MGP_AJ_G0021964
protein coding gene Chr15:73958746-73983733 (+)
AKR/J MGP_AKRJ_G0021947
protein coding gene Chr15:75965620-75990818 (+)
BALB/cJ MGP_BALBcJ_G0021973
protein coding gene Chr15:73984444-74007959 (+)
C3H/HeJ MGP_C3HHeJ_G0021745
protein coding gene Chr15:76010724-76038083 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022413
protein coding gene Chr15:79630847-79658177 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019942
protein coding gene Chr15:70616134-70640902 (+)
CAST/EiJ MGP_CASTEiJ_G0021264
protein coding gene Chr15:76816488-76844439 (+)
CBA/J MGP_CBAJ_G0021712
protein coding gene Chr15:82155705-82179804 (+)
DBA/2J MGP_DBA2J_G0021837
protein coding gene Chr15:73496549-73520474 (+)
FVB/NJ MGP_FVBNJ_G0021817
protein coding gene Chr15:72554028-72578465 (+)
LP/J MGP_LPJ_G0021908
protein coding gene Chr15:76854457-76878084 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021842
protein coding gene Chr15:87487144-87521958 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022433
protein coding gene Chr15:76240444-76265482 (+)
PWK/PhJ MGP_PWKPhJ_G0021005
protein coding gene Chr15:73660962-73685840 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020845
protein coding gene Chr15:75934936-75961335 (+)
WSB/EiJ MGP_WSBEiJ_G0021316
protein coding gene Chr15:76327390-76356698 (+)



Homology
more
  • Human Ortholog
    PPP1R16A, protein phosphatase 1 regulatory subunit 16A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R16A, protein phosphatase 1 regulatory subunit 16A
  • Synonyms
    MYPT3
  • Links
    NCBI Gene ID: 84988
    neXtProt AC: NX_Q96I34
    UniProt: Q96I34

  • Chr Location
    8q24.3; chr8:144477969-144502121 (+)  GRCh38

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    31 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 73062 NCBI Gene Model | MGI Sequence Detail 23277 C57BL/6J ±  kb
transcript NM_001358933 RefSeq | MGI Sequence Detail 2831 ZRU/MplStud  
polypeptide Q923M0 UniProt | EBI | MGI Sequence Detail 524 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013118 protein phosphatase 1 regulatory subunit 16A
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR036770 Ankyrin repeat-containing domain superfamily
    IPR051226 Protein Phosphatase 1 Regulatory Subunit
    IPR017417 Protein phosphatase 1, regulatory subunit 16A/B
  • GlyGen
    Q923M0 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
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  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146326
References
more
  • Summaries
    All 52
    Diseases 1
    Gene Ontology 4
    Phenotypes 31
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory