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Mrgbp Gene Detail
Summary
  • Symbol
    Mrgbp
  • Name
    MRG/MORF4L binding protein
  • Synonyms
    1600027N09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920497
    NCBI Gene: 73247
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:180223097-180228097 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.12 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920497
 protein coding gene Chr2:180222990-180228097 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026996
 protein coding gene Chr2:187111794-187116794 (+)
A/J MGP_AJ_G0026962
 protein coding gene Chr2:179424321-179429322 (+)
AKR/J MGP_AKRJ_G0026932
 protein coding gene Chr2:184803496-184808497 (+)
BALB/cJ MGP_BALBcJ_G0026971
 protein coding gene Chr2:179887001-179892016 (+)
C3H/HeJ MGP_C3HHeJ_G0026712
 protein coding gene Chr2:185153488-185158489 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027417
 protein coding gene Chr2:192513221-192518221 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024782
 protein coding gene Chr2:170116210-170121209 (+)
CAST/EiJ MGP_CASTEiJ_G0026171
 protein coding gene Chr2:183394250-183401203 (+)
CBA/J MGP_CBAJ_G0026689
 protein coding gene Chr2:199512238-199517238 (+)
DBA/2J MGP_DBA2J_G0026827
 protein coding gene Chr2:178521631-178526632 (+)
FVB/NJ MGP_FVBNJ_G0026793
 protein coding gene Chr2:177136456-177141448 (+)
LP/J MGP_LPJ_G0026928
 protein coding gene Chr2:187117901-187122901 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026812
 protein coding gene Chr2:202113748-202118748 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027476
 protein coding gene Chr2:184759578-184764579 (+)
PWK/PhJ MGP_PWKPhJ_G0025907
 protein coding gene Chr2:176033062-176038102 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025707
 protein coding gene Chr2:181251752-181256504 (+)
WSB/EiJ MGP_WSBEiJ_G0026243
 protein coding gene Chr2:185740953-185745993 (+)



Homology
more
  • Human Ortholog
    MRGBP, MRG domain binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRGBP, MRG domain binding protein
  • Synonyms
    C20orf20, Eaf7, MRG15BP, URCC4
  • Links
    NCBI Gene ID: 55257
    neXtProt AC: NX_Q9NV56
    UniProt: Q9NV56

  • Chr Location
    20q13.33; chr20:62796473-62801729 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    48
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027569 Ensembl Gene Model | MGI Sequence Detail 5001 C57BL/6J ±  kb
transcript ENSMUST00000029085 Ensembl | MGI Sequence Detail 1510 Not Applicable  
polypeptide ENSMUSP00000029085 Ensembl | MGI Sequence Detail 204 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139286, MGI:2139504
References
more
  • Summaries
    All 35
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory