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Pradc1 Gene Detail
Summary
  • Symbol
    Pradc1
  • Name
    protease-associated domain containing 1
  • Synonyms
    1700040I03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920577
    NCBI Gene: 73327
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:85423792-85428952 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 37.46 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    150 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920577
 protein coding gene Chr6:85423767-85428969 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030954
 protein coding gene Chr6:86613423-86618569 (-)
A/J MGP_AJ_G0030923
 protein coding gene Chr6:83315501-83320753 (-)
AKR/J MGP_AKRJ_G0030851
 protein coding gene Chr6:85728814-85733954 (-)
BALB/cJ MGP_BALBcJ_G0030933
 protein coding gene Chr6:83308106-83313245 (-)
C3H/HeJ MGP_C3HHeJ_G0030777
 protein coding gene Chr6:98711762-98717724 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031393
 protein coding gene Chr6:88997897-89003039 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028578
 protein coding gene Chr6:81589443-81594163 (-)
CAST/EiJ MGP_CASTEiJ_G0030042
 protein coding gene Chr6:85743823-85748733 (-)
CBA/J MGP_CBAJ_G0030620
 protein coding gene Chr6:92487006-92492143 (-)
DBA/2J MGP_DBA2J_G0030773
 protein coding gene Chr6:82598673-82603810 (-)
FVB/NJ MGP_FVBNJ_G0030726
 protein coding gene Chr6:81800810-81805950 (-)
LP/J MGP_LPJ_G0030852
 protein coding gene Chr6:86609204-86614343 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030762
 protein coding gene Chr6:96691676-96696816 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031417
 protein coding gene Chr6:85529518-85534663 (-)
PWK/PhJ MGP_PWKPhJ_G0029757
 protein coding gene Chr6:81533916-81539050 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029585
 protein coding gene Chr6:84387615-84392763 (-)
WSB/EiJ MGP_WSBEiJ_G0030123
 protein coding gene Chr6:85976651-85983436 (-)



Homology
more
  • Human Ortholog
    PRADC1, protease associated domain containing 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRADC1, protease associated domain containing 1
  • Synonyms
    C2orf7, PAP21
  • Links
    NCBI Gene ID: 84279
    neXtProt AC: NX_Q9BSG0
    UniProt: Q9BSG0

  • Chr Location
    2p13.2; chr2:73228006-73233284 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation results in increased mean serum glucose levels in both males and females when compared with controls.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    2
  • cDNA Data
    43
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030008 Ensembl Gene Model | MGI Sequence Detail 5161 C57BL/6J ±  kb
    transcript ENSMUST00000032080 Ensembl | MGI Sequence Detail 1038 Not Applicable  
    polypeptide ENSMUSP00000032080 Ensembl | MGI Sequence Detail 188 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 43
      cDNA 43

      Microarray probesets 3
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory