Cldn34b2 MGI Mouse Gene Detail - MGI:1920597

Symbol

Cldn34b2
Name

claudin 34B2
Synonyms

1700042B14Rik

Feature Type

protein coding gene
IDs

MGI:1920597
NCBI Gene: 73347
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

ChrX:153907913-153911408 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 72.38 cM, cytoband F3
Mapping Data

2 experiments

SNPs within 2kb

161 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920597	protein coding gene	ChrX:153907913-153930845 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0035865	protein coding gene	ChrX:72146986-72150460 (+)
A/J	MGP_AJ_G0035852	protein coding gene	ChrX:72410269-72414096 (+)
AKR/J	MGP_AKRJ_G0036108	protein coding gene	ChrX:157099846-157103780 (-)
BALB/cJ	MGP_BALBcJ_G0036173	protein coding gene	ChrX:150388944-150391702 (-)
C3H/HeJ	MGP_C3HHeJ_G0035544	protein coding gene	ChrX:72656554-72659983 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0036365	protein coding gene	ChrX:74491854-74492732 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0034830	protein coding gene	ChrX:57960233-57963662 (+)
CBA/J	MGP_CBAJ_G0035517	protein coding gene	ChrX:76437965-76441394 (+)
DBA/2J	MGP_DBA2J_G0035675	protein coding gene	ChrX:71834257-71837686 (+)
FVB/NJ	MGP_FVBNJ_G0035616	protein coding gene	ChrX:71100636-71104065 (+)
LP/J	MGP_LPJ_G0035757	protein coding gene	ChrX:72986694-72993913 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035650	protein coding gene	ChrX:79083449-79087358 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036736	protein coding gene	ChrX:152587789-152591452 (-)
PWK/PhJ	MGP_PWKPhJ_G0034527	protein coding gene	ChrX:56001856-56005673 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0034363	protein coding gene	ChrX:58753066-58756489 (+)
WSB/EiJ	MGP_WSBEiJ_G0034969	protein coding gene	ChrX:71227090-71230363 (+)

Human Ortholog

CLDN34, claudin 34

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CLDN34, claudin 34
Links

HGNC:51259

NCBI Gene ID: 100288814

neXtProt AC: NX_H7C241

UniProt: H7C241
Chr Location

chrX:9967358-9968352 (+) GRCh38

MGI Vertebrate Homology

Cldn34b2 stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: CLDN34
Gene Tree

Cldn34b2

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Endonuclease-mediated

1
Targeted

2
Find Mice (IMSR)

7 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

4
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

4

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

32
RefSeq

7
UniProt

1
CCDS

CCDS53232.1

Ensembl

ENSMUSG00000057402 (Evidence)
NCBI Gene

73347

			Length	Strain/Species	Flank
genomic	ENSMUSG00000057402	Ensembl Gene Model \| MGI Sequence Detail	3496	C57BL/6J	± kb
transcript	ENSMUST00000076671	Ensembl \| MGI Sequence Detail	1077	Not Applicable
polypeptide	ENSMUSP00000075967	Ensembl \| MGI Sequence Detail	209	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR006187 Claudin

IPR004031 PMP-22/EMP/MP20/Claudin

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All nucleic 4

cDNA 4

Microarray probesets 3

Summaries

All 25

Gene Ontology 1

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Cldn34b2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr164429	ChrX:153911405-153911436 (-)	-13 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24