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Bpifa3 Gene Detail
Summary
  • Symbol
    Bpifa3
  • Name
    BPI fold containing family A, member 3
  • Synonyms
    1700058C13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920638
    NCBI Gene: 73388
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:153972256-153980276 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 76.15 cM, cytoband H2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    310 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920638
 protein coding gene Chr2:153972222-153980279 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026706
 protein coding gene Chr2:158850613-158858621 (+)
A/J MGP_AJ_G0026672
 protein coding gene Chr2:152455832-152463779 (+)
AKR/J MGP_AKRJ_G0026643
 protein coding gene Chr2:156938784-156946809 (+)
BALB/cJ MGP_BALBcJ_G0026682
 protein coding gene Chr2:152807763-152815788 (+)
C3H/HeJ MGP_C3HHeJ_G0026424
 protein coding gene Chr2:157320002-157328040 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027131
 protein coding gene Chr2:163474350-163482360 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024501
 protein coding gene Chr2:146053835-146062694 (+)
CAST/EiJ MGP_CASTEiJ_G0025885
 protein coding gene Chr2:157642070-157650100 (+)
CBA/J MGP_CBAJ_G0026403
 protein coding gene Chr2:169474056-169482093 (+)
DBA/2J MGP_DBA2J_G0026538
 protein coding gene Chr2:151719882-151727829 (+)
FVB/NJ MGP_FVBNJ_G0026504
 protein coding gene Chr2:150125880-150133890 (+)
LP/J MGP_LPJ_G0026643
 protein coding gene Chr2:158950545-158958553 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026526
 protein coding gene Chr2:173503279-173511226 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027186
 protein coding gene Chr2:156820166-156828188 (+)
PWK/PhJ MGP_PWKPhJ_G0025619
 protein coding gene Chr2:151274695-151282686 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025422
 protein coding gene Chr2:155761911-155769942 (+)
WSB/EiJ MGP_WSBEiJ_G0025955
 protein coding gene Chr2:157738959-157747035 (+)



Homology
more
  • Human Ortholog
    BPIFA3, BPI fold containing family A member 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BPIFA3, BPI fold containing family A member 3
  • Synonyms
    C20orf71, SPLUNC3
  • Links
    NCBI Gene ID: 128861
    neXtProt AC: NX_Q9BQP9
    UniProt: Q9BQP9

  • Chr Location
    20q11.21; chr20:33217310-33227806 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027482 Ensembl Gene Model | MGI Sequence Detail 8021 C57BL/6J ±  kb
transcript ENSMUST00000028984 Ensembl | MGI Sequence Detail 1107 Not Applicable  
polypeptide ENSMUSP00000028984 Ensembl | MGI Sequence Detail 239 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015549 BPI fold-containing family A member 3
    (term hierarchy)
  • InterPro Domains
    IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
    IPR032946 BPI fold-containing family A member 3
    IPR017942 Lipid-binding serum glycoprotein, N-terminal
  • GlyGen
    Q9D9J8 3 sites
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory