About   Help   FAQ
Chct1 Gene Detail
Summary
  • Symbol
    Chct1
  • Name
    CHD1 helical C-terminal domain containing 1
  • Synonyms
    1700125H20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920884
    NCBI Gene: 73634
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:85061230-85071971 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.34 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920884
 protein coding gene Chr11:85031023-85072042 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018879
 protein coding gene Chr11:86657902-86669944 (+)
A/J MGP_AJ_G0018846
 protein coding gene Chr11:83334517-83346874 (+)
AKR/J MGP_AKRJ_G0018816
 protein coding gene Chr11:85816123-85826995 (+)
BALB/cJ MGP_BALBcJ_G0018819
 protein coding gene Chr11:83723693-83737695 (+)
C3H/HeJ MGP_C3HHeJ_G0018633
 protein coding gene Chr11:85856230-85866687 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019271
 protein coding gene Chr11:89275244-89303505 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016904
 protein coding gene Chr11:80397620-80407937 (+)
CAST/EiJ MGP_CASTEiJ_G0018188
 protein coding gene Chr11:86503219-86514321 (+)
CBA/J MGP_CBAJ_G0018604
 protein coding gene Chr11:93084193-93098695 (+)
DBA/2J MGP_DBA2J_G0018712
 protein coding gene Chr11:82912729-82923632 (+)
FVB/NJ MGP_FVBNJ_G0018701
 protein coding gene Chr11:82397751-82408189 (+)
LP/J MGP_LPJ_G0018782
 protein coding gene Chr11:87163458-87173887 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018728
 protein coding gene Chr11:93221771-93231985 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019311
 protein coding gene Chr11:86076059-86087754 (+)
PWK/PhJ MGP_PWKPhJ_G0017957
 protein coding gene Chr11:83687229-83697737 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017749
 protein coding gene Chr11:85634283-85647587 (+)
WSB/EiJ MGP_WSBEiJ_G0018239
 protein coding gene Chr11:85926276-85936761 (+)



Homology
more
  • Human Ortholog
    CHCT1, CHD1 helical C-terminal domain containing 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHCT1, CHD1 helical C-terminal domain containing 1
  • Synonyms
    C17orf64
  • Links
    NCBI Gene ID: 124773
    neXtProt AC: NX_Q86WR6
    UniProt: Q86WR6

  • Chr Location
    17q23.2; chr17:60392429-60431426 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    5
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000018479 Ensembl Gene Model | MGI Sequence Detail 10742 C57BL/6J ±  kb
    transcript ENSMUST00000018623 Ensembl | MGI Sequence Detail 966 Not Applicable  
    polypeptide ENSMUSP00000018623 Ensembl | MGI Sequence Detail 236 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000059904 CHD1 helical C-terminal domain containing protein 1
      (term hierarchy)
    • InterPro Domains
      IPR039880 CHD1 helical C-terminal domain containing protein 1-like
      IPR025260 Chromodomain-helicase-DNA-binding protein 1-like, C-terminal domain
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:7328943
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 18
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory