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Cabp4 Gene Detail
Summary
  • Symbol
    Cabp4
  • Name
    calcium binding protein 4
  • Synonyms
    2410038D05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920910
    NCBI Gene: 73660
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr19:4185422-4189608 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 3.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920910
 protein coding gene Chr19:4185422-4194032 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024648
 protein coding gene Chr19:970535-977177 (-)
A/J MGP_AJ_G0024614
 protein coding gene Chr19:937331-941130 (-)
AKR/J MGP_AKRJ_G0024587
 protein coding gene Chr19:961613-966449 (-)
BALB/cJ MGP_BALBcJ_G0024614
 protein coding gene Chr19:925513-930135 (-)
C3H/HeJ MGP_C3HHeJ_G0024382
 protein coding gene Chr19:957262-961621 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025062
 protein coding gene Chr19:1010551-1017456 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022491
 protein coding gene Chr19:879489-883649 (-)
CAST/EiJ MGP_CASTEiJ_G0023854
 protein coding gene Chr19:965416-971371 (-)
CBA/J MGP_CBAJ_G0024353
 protein coding gene Chr19:1067331-1072537 (-)
DBA/2J MGP_DBA2J_G0024481
 protein coding gene Chr19:896347-901022 (-)
FVB/NJ MGP_FVBNJ_G0024448
 protein coding gene Chr19:906495-911291 (-)
LP/J MGP_LPJ_G0024567
 protein coding gene Chr19:965240-969958 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024478
 protein coding gene Chr19:1016081-1020208 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025109
 protein coding gene Chr19:958148-962917 (-)
PWK/PhJ MGP_PWKPhJ_G0023600
 protein coding gene Chr19:948423-953246 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023405
 protein coding gene Chr19:939150-943318 (-)
WSB/EiJ MGP_WSBEiJ_G0023916
 protein coding gene Chr19:945322-951248 (-)



Homology
more
  • Human Ortholog
    CABP4, calcium binding protein 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CABP4, calcium binding protein 4
  • Synonyms
    CRSD, CSNB2B
  • Links
    NCBI Gene ID: 57010
    neXtProt AC: NX_P57796
    UniProt: P57796

  • Chr Location
    11q13.2; chr11:67452403-67461752 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with disruptions in this gene display structural and electrophysiological abnormalities in the retina.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    14
  • cDNA Data
    16
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 73660 NCBI Gene Model | MGI Sequence Detail 4187 C57BL/6J ±  kb
    transcript NM_144532 RefSeq | MGI Sequence Detail 1472 Not Specified  
    polypeptide Q8VHC5 UniProt | EBI | MGI Sequence Detail 271 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 2
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 12
    • Earliest
      J:59389 Haeseleer F, et al., Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin. J Biol Chem. 2000 Jan 14;275(2):1247-60
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory