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Tmem198b Gene Detail
Summary
  • Symbol
    Tmem198b
  • Name
    transmembrane protein 198b
  • Synonyms
    1110012D08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921077
    NCBI Gene: 73827
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128635905-128640239 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 77.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    149 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921077
 protein coding gene Chr10:128633958-128641255 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017883
 protein coding gene Chr10:132593382-132597716 (-)
A/J MGP_AJ_G0017858
 protein coding gene Chr10:127255106-127259440 (-)
AKR/J MGP_AKRJ_G0017821
 protein coding gene Chr10:130973503-130977837 (-)
BALB/cJ MGP_BALBcJ_G0017822
 protein coding gene Chr10:127619207-127623137 (-)
C3H/HeJ MGP_C3HHeJ_G0017645
 protein coding gene Chr10:131141736-131146070 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018277
 protein coding gene Chr10:137059306-137063640 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015955
 protein coding gene Chr10:121168662-121173031 (-)
CAST/EiJ MGP_CASTEiJ_G0017206
 protein coding gene Chr10:131865926-131870214 (-)
CBA/J MGP_CBAJ_G0017615
 protein coding gene Chr10:142652101-142656435 (-)
DBA/2J MGP_DBA2J_G0017721
 protein coding gene Chr10:126311954-126318076 (-)
FVB/NJ MGP_FVBNJ_G0017716
 protein coding gene Chr10:125236065-125240399 (-)
LP/J MGP_LPJ_G0017795
 protein coding gene Chr10:133167706-133172040 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017744
 protein coding gene Chr10:145211447-145215781 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018317
 protein coding gene Chr10:131077808-131082142 (-)
PWK/PhJ MGP_PWKPhJ_G0016991
 protein coding gene Chr10:126579965-126584299 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016780
 protein coding gene Chr10:130185854-130191266 (-)
WSB/EiJ MGP_WSBEiJ_G0017265
 protein coding gene Chr10:131306036-131310402 (-)



Homology
more
  • Human Ortholog
    TMEM198B, transmembrane protein 198B (pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM198B, transmembrane protein 198B (pseudogene)
  • Links
    NCBI Gene ID: 440104

  • Chr Location
    12q13.2; chr12:55829608-55836253 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice exhibit impaired sensorimotor gating/attention during prepulse inhibition testing compared with wild-type littermates.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    21
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047090 Ensembl Gene Model | MGI Sequence Detail 4335 C57BL/6J ±  kb
transcript ENSMUST00000051011 Ensembl | MGI Sequence Detail 2335 Not Applicable  
polypeptide ENSMUSP00000050451 Ensembl | MGI Sequence Detail 350 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR025256 Domain of unknown function DUF4203
    IPR040236 Transmembrane protein 198
  • GlyGen
    Q8CFU0 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 5
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory