Spmip11 MGI Mouse Gene Detail - MGI:1921113 - sperm microtubule inner protein 11

Symbol

Spmip11
Name

sperm microtubule inner protein 11
Synonyms

4930415O20Rik, Tex49

Feature Type

protein coding gene
IDs

MGI:1921113
NCBI Gene: 73863
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr15:98468885-98487461 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 54.57 cM, cytoband F2
Mapping Data

2 experiments

SNPs within 2kb

555 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921113	protein coding gene	Chr15:98468885-98487469 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0022302	protein coding gene	Chr15:100307357-100325554 (+)
A/J	MGP_AJ_G0022260	protein coding gene	Chr15:96350434-96368405 (+)
AKR/J	MGP_AKRJ_G0022235	protein coding gene	Chr15:99320699-99338763 (+)
BALB/cJ	MGP_BALBcJ_G0022267	protein coding gene	Chr15:96547681-96566846 (+)
C3H/HeJ	MGP_C3HHeJ_G0022035	protein coding gene	Chr15:99360118-99379635 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0022712	protein coding gene	Chr15:104019330-104043622 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020237	protein coding gene	Chr15:92270408-92288464 (+)
CAST/EiJ	MGP_CASTEiJ_G0021558	protein coding gene	Chr15:100213963-100233741 (+)
CBA/J	MGP_CBAJ_G0022004	protein coding gene	Chr15:107553398-107577517 (+)
DBA/2J	MGP_DBA2J_G0022130	protein coding gene	Chr15:95796768-95815690 (+)
FVB/NJ	MGP_FVBNJ_G0022110	protein coding gene	Chr15:94768787-94787484 (+)
LP/J	MGP_LPJ_G0022202	protein coding gene	Chr15:100462709-100483219 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022130	protein coding gene	Chr15:111574011-111594256 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022727	protein coding gene	Chr15:99393974-99414933 (+)
PWK/PhJ	MGP_PWKPhJ_G0021299	protein coding gene	Chr15:95914018-95933267 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0021134	protein coding gene	Chr15:99235990-99259450 (+)
WSB/EiJ	MGP_WSBEiJ_G0021608	protein coding gene	Chr15:99940157-99961084 (+)

Human Ortholog

SPMIP11, sperm microtubule inner protein 11

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SPMIP11, sperm microtubule inner protein 11
Synonyms

LINC00935, TEX49
Links

HGNC:48628

NCBI Gene ID: 255411

UniProt: A0A1B0GTD5
Chr Location

12q13.12; chr12:48727435-48771459 (+) GRCh38

MGI Vertebrate Homology

Spmip11 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SPMIP11
Gene Tree

Spmip11

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References

1 with disease annotations

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Phenotype Summary

23 phenotype references

All Mutations and Alleles

38
Chemically induced (other)

1
Gene trapped

34
Radiation induced

2
Targeted

1
Genomic Mutations

3 involving Spmip11
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

8 strains or lines available

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All GO Annotations

2
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

9

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

29
RefSeq

2
UniProt

1
CCDS

CCDS49722.1

Ensembl

ENSMUSG00000022993 (Evidence)
NCBI Gene

73863

			Length	Strain/Species	Flank
genomic	ENSMUSG00000022993	Ensembl Gene Model \| MGI Sequence Detail	18577	C57BL/6J	± kb
transcript	ENSMUST00000023728	Ensembl \| MGI Sequence Detail	558	Not Applicable
polypeptide	ENSMUSP00000023728	Ensembl \| MGI Sequence Detail	131	Not Applicable

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UniProt

1 Sequence
PDB

8IYJ
InterPro Domains

IPR038775 Sperm microtubule inner protein 11

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All nucleic 9

cDNA 9

Microarray probesets 2

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MGI:6456108, MGI:7470732

Summaries

All 42

Diseases 1

Gene Ontology 2

Phenotypes 23
Earliest

J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
Latest

J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19

TSS for Spmip11:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr132947	Chr15:98468888-98468907 (+)	13 bp
Tssr132948	Chr15:98468921-98468926 (+)	39 bp
Tssr132949	Chr15:98468930-98468940 (+)	50 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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