Stra6l MGI Mouse Gene Detail - MGI:1921402

Symbol

Stra6l
Name

STRA6-like
Synonyms

1300002K09Rik, Rbpr2

Feature Type

protein coding gene
IDs

MGI:1921402
NCBI Gene: 74152
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr4:45848664-45887008 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 24.39 cM, cytoband B2
Mapping Data

2 experiments

SNPs within 2kb

1461 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921402	protein coding gene	Chr4:45818940-45887010 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028248	protein coding gene	Chr4:44107032-44152671 (+)
A/J	MGP_AJ_G0028207	protein coding gene	Chr4:42522495-42560588 (+)
AKR/J	MGP_AKRJ_G0028157	protein coding gene	Chr4:43538079-43579531 (+)
BALB/cJ	MGP_BALBcJ_G0028227	protein coding gene	Chr4:42606533-42645246 (+)
C3H/HeJ	MGP_C3HHeJ_G0027948	protein coding gene	Chr4:44146447-44191367 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0028668	protein coding gene	Chr4:45747665-45795797 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025977	protein coding gene	Chr4:39908104-39947222 (+)
CAST/EiJ	MGP_CASTEiJ_G0027387	protein coding gene	Chr4:43701816-43744057 (+)
CBA/J	MGP_CBAJ_G0027914	protein coding gene	Chr4:47180749-47230535 (+)
DBA/2J	MGP_DBA2J_G0028064	protein coding gene	Chr4:42414635-42453705 (+)
FVB/NJ	MGP_FVBNJ_G0028031	protein coding gene	Chr4:41655023-41693972 (+)
LP/J	MGP_LPJ_G0028163	protein coding gene	Chr4:44168016-44208381 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028055	protein coding gene	Chr4:50309567-50353340 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028703	protein coding gene	Chr4:43761662-43804890 (+)
PWK/PhJ	MGP_PWKPhJ_G0027112	protein coding gene	Chr4:42496946-42535947 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026940	protein coding gene	Chr4:43256364-43297665 (+)
WSB/EiJ	MGP_WSBEiJ_G0027465	protein coding gene	Chr4:43657621-43699975 (+)

Human Ortholog

STRA6LP, STRA6 like, pseudogene

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

STRA6LP, STRA6 like, pseudogene
Links

HGNC:53830

NCBI Gene ID: 112272565
Chr Location

9q22.33; chr9:97290853-97294111 (+) GRCh38

MGI Vertebrate Homology

Stra6l stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: STRA6LP
Gene Tree

Stra6l

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Endonuclease-mediated

1
Gene trapped

1
Targeted

4
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

27 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

9
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

728
Tissues

13
cDNA Data

17
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase stra6l

ZFIN stra6l

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All Sequences

62
RefSeq

20
UniProt

2
CCDS

CCDS18141.1, CCDS80094.1

Ensembl

ENSMUSG00000028327 (Evidence)
NCBI Gene

74152

			Length	Strain/Species	Flank
genomic	ENSMUSG00000028327	Ensembl Gene Model \| MGI Sequence Detail	38345	C57BL/6J	± kb
transcript	ENSMUST00000107783	Ensembl \| MGI Sequence Detail	3669	Not Applicable
polypeptide	ENSMUSP00000103412	Ensembl \| MGI Sequence Detail	621	Not Applicable

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UniProt

2 Sequences
InterPro Domains

IPR026612 Receptor for retinol uptake STRA6-like
GlyGen

Q9DBN1 2 sites, 1 O-linked glycan (1 site)

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All nucleic 17

cDNA 17

Microarray probesets 3

Summaries

All 31

Developmental Gene Expression 2

Gene Ontology 3

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Stra6l:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr37074	Chr4:45848326-45848374 (+)	-314 bp
Tssr37075	Chr4:45848675-45848696 (+)	22 bp
Tssr37076	Chr4:45848883-45848910 (+)	233 bp
Tssr37077	Chr4:45848920-45848950 (+)	271 bp
Tssr37078	Chr4:45848958-45849016 (+)	323 bp
Tssr37079	Chr4:45849021-45849037 (+)	365 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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