Sertad4b MGI Mouse Gene Detail - MGI:1921534

Symbol

Sertad4b
Name

SERTA domain containing 4B
Synonyms

1700006L05Rik, 1700086L19Rik

Feature Type

protein coding gene

BioType Conflict
IDs

MGI:1921534
NCBI Gene: 74284
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr12:74331050-74342724 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 32.45 cM
Mapping Data

2 experiments

SNPs within 2kb

280 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921534	protein coding gene	Chr12:74331016-74342724 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0005366	lincRNA gene	Chr12:74247403-74258939 (+)
A/J	MGP_AJ_G0005349	lincRNA gene	Chr12:71471320-71483072 (+)
AKR/J	MGP_AKRJ_G0005329	lincRNA gene	Chr12:73615964-73628594 (+)
BALB/cJ	MGP_BALBcJ_G0005331	lincRNA gene	Chr12:71938445-71950421 (+)
C3H/HeJ	MGP_C3HHeJ_G0005280	lincRNA gene	Chr12:74075106-74087594 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0005485	lincRNA gene	Chr12:76531561-76543208 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0004872	lincRNA gene	Chr12:68881238-68892361 (+)
CAST/EiJ	MGP_CASTEiJ_G0005227	lincRNA gene	Chr12:68860713-68874282 (+)
CBA/J	MGP_CBAJ_G0005269	lincRNA gene	Chr12:79502432-79514511 (+)
DBA/2J	MGP_DBA2J_G0005287	lincRNA gene	Chr12:71336237-71348348 (+)
FVB/NJ	MGP_FVBNJ_G0005312	lincRNA gene	Chr12:70181949-70194745 (+)
LP/J	MGP_LPJ_G0005368	lincRNA gene	Chr12:74255295-74267316 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0005294	lincRNA gene	Chr12:82566538-82578869 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0005487	lincRNA gene	Chr12:73109012-73121300 (+)
PWK/PhJ	MGP_PWKPhJ_G0005176	lincRNA gene	Chr12:65673367-65685394 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0005096	lincRNA gene	Chr12:67550247-67565957 (+)
WSB/EiJ	MGP_WSBEiJ_G0005275	lincRNA gene	Chr12:73705144-73716698 (+)

Human Ortholog

SERTAD4BP, SERTA domain containing 4B, pseudogene

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SERTAD4BP, SERTA domain containing 4B, pseudogene
Synonyms

LINC00643
Links

HGNC:44296

NCBI Gene ID: 646113
Chr Location

chr14:62117346-62134186 (+) GRCh38

MGI Vertebrate Homology

Sertad4b stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: SERTAD4BP
Gene Tree

Sertad4b

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Chemically induced (other)

1
Targeted

3
Genomic Mutations

1 involving Sertad4b
Find Mice (IMSR)

5 strains or lines available

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

827
Tissues

111
cDNA Data

6
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

32
RefSeq

3

Ensembl

ENSMUSG00000071265 (Evidence)
NCBI Gene

74284

Representative Sequences				Length	Strain/Species	Flank
	genomic	74284	NCBI Gene Model \| MGI Sequence Detail	11675	C57BL/6J	± kb
	transcript	NR_030733	RefSeq \| MGI Sequence Detail	1063	C57BL/6

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All nucleic 8

cDNA 6

Primer pair 1

Other 1

Microarray probesets 3

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MGI:1916530, MGI:2144940, MGI:7716858

Summaries

All 27

Developmental Gene Expression 3

Phenotypes 8
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Sertad4b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr113882	Chr12:74331045-74331084 (+)	15 bp
Tssr113883	Chr12:74331092-74331104 (+)	48 bp
Tssr113884	Chr12:74331122-74331127 (+)	75 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24