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Snx11 Gene Detail
Summary
  • Symbol
    Snx11
  • Name
    sorting nexin 11
  • Synonyms
    4933439F10Rik, A930041K09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921729
    NCBI Gene: 74479
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96658381-96668385 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 60.10 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    265 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921729
 protein coding gene Chr11:96658372-96668538 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019011
 protein coding gene Chr11:99114833-99124833 (-)
A/J MGP_AJ_G0018979
 protein coding gene Chr11:95055645-95065583 (-)
AKR/J MGP_AKRJ_G0018949
 protein coding gene Chr11:97997729-98007743 (-)
BALB/cJ MGP_BALBcJ_G0018952
 protein coding gene Chr11:95555687-95565686 (-)
C3H/HeJ MGP_C3HHeJ_G0018766
 protein coding gene Chr11:98130246-98140246 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019404
 protein coding gene Chr11:102197636-102207640 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017034
 protein coding gene Chr11:92537928-92548256 (-)
CAST/EiJ MGP_CASTEiJ_G0018319
 protein coding gene Chr11:98966408-98976408 (-)
CBA/J MGP_CBAJ_G0018737
 protein coding gene Chr11:106374896-106384834 (-)
DBA/2J MGP_DBA2J_G0018845
 protein coding gene Chr11:94618201-94628272 (-)
FVB/NJ MGP_FVBNJ_G0018834
 protein coding gene Chr11:94096856-94106860 (-)
LP/J MGP_LPJ_G0018915
 protein coding gene Chr11:99636096-99646096 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018861
 protein coding gene Chr11:106340492-106350474 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019444
 protein coding gene Chr11:98302301-98312301 (-)
PWK/PhJ MGP_PWKPhJ_G0018091
 protein coding gene Chr11:95585600-95595642 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017880
 protein coding gene Chr11:98030253-98041815 (-)
WSB/EiJ MGP_WSBEiJ_G0018369
 protein coding gene Chr11:98210309-98220308 (-)



Homology
more
  • Human Ortholog
    SNX11, sorting nexin 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNX11, sorting nexin 11
  • Links
    NCBI Gene ID: 29916
    neXtProt AC: NX_Q9Y5W9
    UniProt: Q9Y5W9

  • Chr Location
    17q21.32; chr17:48103357-48123601 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased thermosensation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    8
  • cDNA Data
    50
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020876 Ensembl Gene Model | MGI Sequence Detail 10005 C57BL/6J ±  kb
transcript ENSMUST00000021246 Ensembl | MGI Sequence Detail 2551 Not Applicable  
polypeptide ENSMUSP00000021246 Ensembl | MGI Sequence Detail 271 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925090, MGI:2144070
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 14
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:309511 Huang HL, et al., Sorting nexin 11 knockout mice exhibit enhanced thermosensing behaviour. Genes Brain Behav. 2020 Jul;19(6):e12625
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory