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Rasgef1c Gene Detail
Summary
  • Symbol
    Rasgef1c
  • Name
    RasGEF domain family, member 1C
  • Synonyms
    9130006A14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921813
    NCBI Gene: 74563
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:49791996-49871050 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 30.02 cM, cytoband B1.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2248 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921813
 protein coding gene Chr11:49791996-49871821 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018239
 protein coding gene Chr11:49053574-49128346 (+)
A/J MGP_AJ_G0018207
 protein coding gene Chr11:47176719-47250347 (+)
AKR/J MGP_AKRJ_G0018177
 protein coding gene Chr11:48680684-48753720 (+)
BALB/cJ MGP_BALBcJ_G0018177
 protein coding gene Chr11:47452322-47525774 (+)
C3H/HeJ MGP_C3HHeJ_G0017990
 protein coding gene Chr11:48672035-48746306 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018628
 protein coding gene Chr11:50516187-50593615 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016280
 protein coding gene Chr11:44791600-44866691 (+)
CAST/EiJ MGP_CASTEiJ_G0017552
 protein coding gene Chr11:48644768-48728227 (+)
CBA/J MGP_CBAJ_G0017965
 protein coding gene Chr11:52842840-52918586 (+)
DBA/2J MGP_DBA2J_G0018072
 protein coding gene Chr11:46975784-47051616 (+)
FVB/NJ MGP_FVBNJ_G0018066
 protein coding gene Chr11:46594038-46667220 (+)
LP/J MGP_LPJ_G0018147
 protein coding gene Chr11:49389305-49467590 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018091
 protein coding gene Chr11:54395587-54469027 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018672
 protein coding gene Chr11:48778489-48852609 (+)
PWK/PhJ MGP_PWKPhJ_G0017330
 protein coding gene Chr11:47366536-47441664 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017125
 protein coding gene Chr11:48478031-48549659 (+)
WSB/EiJ MGP_WSBEiJ_G0017605
 protein coding gene Chr11:48426147-48500744 (+)



Homology
more
  • Human Ortholog
    RASGEF1C, RasGEF domain family member 1C
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASGEF1C, RasGEF domain family member 1C
  • Links
    NCBI Gene ID: 255426
    neXtProt AC: NX_Q8N431
    UniProt: Q8N431

  • Chr Location
    5q35.3; chr5:180100795-180209211 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    3
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74563 NCBI Gene Model | MGI Sequence Detail 79055 C57BL/6J ±  kb
transcript NM_001347462 RefSeq | MGI Sequence Detail 2611 C57BL/6  
polypeptide Q9D300 UniProt | EBI | MGI Sequence Detail 466 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013755 Ras-GEF domain-containing family member 1C
    (term hierarchy)
  • InterPro Domains
    IPR036964 Ras guanine-nucleotide exchange factor, catalytic domain superfamily
    IPR019804 Ras guanine-nucleotide exchange factor, conserved site
    IPR023578 Ras guanine nucleotide exchange factor domain superfamily
    IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
    IPR008937 Ras-like guanine nucleotide exchange factor
    IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
Molecular
Reagents
less
  • All nucleic 12
    Genomic 1
    cDNA 11

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory