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Ttc17 Gene Detail
Summary
  • Symbol
    Ttc17
  • Name
    tetratricopeptide repeat domain 17
  • Synonyms
    9130020K17Rik, D2Bwg1005e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921819
    NCBI Gene: 74569
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:94131112-94237034 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 51.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3004 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921819
 protein coding gene Chr2:94131111-94237034 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026185
 protein coding gene Chr2:95842626-95956562 (-)
A/J MGP_AJ_G0026146
 protein coding gene Chr2:91940444-92047835 (-)
AKR/J MGP_AKRJ_G0026127
 protein coding gene Chr2:94519838-94628194 (-)
BALB/cJ MGP_BALBcJ_G0026155
 protein coding gene Chr2:92141337-92247685 (-)
C3H/HeJ MGP_C3HHeJ_G0025906
 protein coding gene Chr2:94786576-94895324 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026606
 protein coding gene Chr2:99087271-99212315 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023997
 protein coding gene Chr2:88420020-88523850 (-)
CAST/EiJ MGP_CASTEiJ_G0025371
 protein coding gene Chr2:95409176-95520687 (-)
CBA/J MGP_CBAJ_G0025884
 protein coding gene Chr2:102562875-102686275 (-)
DBA/2J MGP_DBA2J_G0026020
 protein coding gene Chr2:91553255-91659176 (-)
FVB/NJ MGP_FVBNJ_G0025983
 protein coding gene Chr2:90670081-90776668 (-)
LP/J MGP_LPJ_G0026124
 protein coding gene Chr2:96037985-96147791 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026009
 protein coding gene Chr2:105452299-105561208 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026660
 protein coding gene Chr2:94607620-94722062 (-)
PWK/PhJ MGP_PWKPhJ_G0025106
 protein coding gene Chr2:91305959-91416856 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024907
 protein coding gene Chr2:94167974-94276292 (-)
WSB/EiJ MGP_WSBEiJ_G0025438
 protein coding gene Chr2:95220372-95328076 (-)



Homology
more
  • Human Ortholog
    TTC17, tetratricopeptide repeat domain 17
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TTC17, tetratricopeptide repeat domain 17
  • Links
    NCBI Gene ID: 55761
    neXtProt AC: NX_Q96AE7
    UniProt: Q96AE7

  • Chr Location
    11p12-p11.2; chr11:43358920-43494933 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027194 Ensembl Gene Model | MGI Sequence Detail 105923 C57BL/6J ±  kb
    transcript ENSMUST00000111238 Ensembl | MGI Sequence Detail 4590 Not Applicable  
    polypeptide ENSMUSP00000106869 Ensembl | MGI Sequence Detail 1198 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000032051 tetratricopeptide repeat protein 17
      (term hierarchy)
    • InterPro Domains
      IPR011990 Tetratricopeptide-like helical domain superfamily
      IPR019734 Tetratricopeptide repeat
      IPR052630 Tetratricopeptide repeat protein 17
    • GlyGen
      E9PVB5 5 sites, 6 N-linked glycans (5 sites)
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 11
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-34255, MGI:106561
    References
    more
    • Summaries
      All 38
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory