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Pyroxd2 Gene Detail
Summary
  • Symbol
    Pyroxd2
  • Name
    pyridine nucleotide-disulphide oxidoreductase domain 2
  • Synonyms
    3830409H07Rik, 4833409A17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921830
    NCBI Gene: 74580
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:42714297-42741214 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 36.56 cM, cytoband D1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1056 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921830
 protein coding gene Chr19:42714296-42741261 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025148
 protein coding gene Chr19:42074150-42106811 (-)
A/J MGP_AJ_G0025125
 protein coding gene Chr19:40054327-40081940 (-)
AKR/J MGP_AKRJ_G0025093
 protein coding gene Chr19:41345302-41378861 (-)
BALB/cJ MGP_BALBcJ_G0025119
 protein coding gene Chr19:40120303-40150068 (-)
C3H/HeJ MGP_C3HHeJ_G0024879
 protein coding gene Chr19:41507439-41536824 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025562
 protein coding gene Chr19:43154332-43181246 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022976
 protein coding gene Chr19:39406132-39433439 (-)
CAST/EiJ MGP_CASTEiJ_G0024344
 protein coding gene Chr19:41206499-41235164 (-)
CBA/J MGP_CBAJ_G0024859
 protein coding gene Chr19:45247746-45281203 (-)
DBA/2J MGP_DBA2J_G0024991
 protein coding gene Chr19:39893875-39921776 (-)
FVB/NJ MGP_FVBNJ_G0024952
 protein coding gene Chr19:39672998-39701237 (-)
LP/J MGP_LPJ_G0025077
 protein coding gene Chr19:42056265-42087146 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024983
 protein coding gene Chr19:44841675-44872550 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025620
 protein coding gene Chr19:41420950-41450044 (-)
PWK/PhJ MGP_PWKPhJ_G0024093
 protein coding gene Chr19:39796762-39824959 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023897
 protein coding gene Chr19:40167291-40194257 (-)
WSB/EiJ MGP_WSBEiJ_G0024414
 protein coding gene Chr19:41556773-41588388 (-)



Homology
more
  • Human Ortholog
    PYROXD2, pyridine nucleotide-disulphide oxidoreductase domain 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PYROXD2, pyridine nucleotide-disulphide oxidoreductase domain 2
  • Synonyms
    C10orf33, FP3420, YUEF
  • Links
    NCBI Gene ID: 84795
    neXtProt AC: NX_Q8N2H3
    UniProt: Q8N2H3

  • Chr Location
    10q24.2; chr10:98383565-98415182 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060224 Ensembl Gene Model | MGI Sequence Detail 26918 C57BL/6J ±  kb
transcript ENSMUST00000236659 Ensembl | MGI Sequence Detail 3137 Not Applicable  
polypeptide ENSMUSP00000157893 Ensembl | MGI Sequence Detail 587 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    Genomic 2
    cDNA 5

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917948
References
more
  • Summaries
    All 26
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory