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Spsb1 Gene Detail
Summary
  • Symbol
    Spsb1
  • Name
    splA/ryanodine receptor domain and SOCS box containing 1
  • Synonyms
    1110014L01Rik, 4930422J18Rik, SSB1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921896
    NCBI Gene: 74646
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:149980740-150039494 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 80.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    545 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921896
 protein coding gene Chr4:149980740-150039500 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029147
 protein coding gene Chr4:153809737-153873930 (-)
A/J MGP_AJ_G0029112
 protein coding gene Chr4:147367367-147427305 (-)
AKR/J MGP_AKRJ_G0029060
 protein coding gene Chr4:151418055-151478739 (-)
BALB/cJ MGP_BALBcJ_G0029128
 protein coding gene Chr4:147860848-147928442 (-)
C3H/HeJ MGP_C3HHeJ_G0028849
 protein coding gene Chr4:151951589-152012450 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029577
 protein coding gene Chr4:159351056-159417253 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026823
 protein coding gene Chr4:139779302-139836884 (-)
CAST/EiJ MGP_CASTEiJ_G0028262
 protein coding gene Chr4:149202508-149260711 (-)
CBA/J MGP_CBAJ_G0028811
 protein coding gene Chr4:164025329-164097704 (-)
DBA/2J MGP_DBA2J_G0028960
 protein coding gene Chr4:147466826-147525582 (-)
FVB/NJ MGP_FVBNJ_G0028924
 protein coding gene Chr4:146587499-146647409 (-)
LP/J MGP_LPJ_G0029050
 protein coding gene Chr4:153724813-153784568 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028951
 protein coding gene Chr4:167220029-167283272 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029609
 protein coding gene Chr4:151908281-151974037 (-)
PWK/PhJ MGP_PWKPhJ_G0027982
 protein coding gene Chr4:143477955-143538467 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027816
 protein coding gene Chr4:146166911-146229302 (-)
WSB/EiJ MGP_WSBEiJ_G0028342
 protein coding gene Chr4:152055799-152117753 (-)



Homology
more
  • Human Ortholog
    SPSB1, splA/ryanodine receptor domain and SOCS box containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPSB1, splA/ryanodine receptor domain and SOCS box containing 1
  • Synonyms
    SSB-1, SSB1
  • Links
    NCBI Gene ID: 80176
    neXtProt AC: NX_Q96BD6
    UniProt: Q96BD6

  • Chr Location
    1p36.22; chr1:9292894-9369532 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    45
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74646 NCBI Gene Model | MGI Sequence Detail 58755 C57BL/6J ±  kb
transcript NM_001419256 RefSeq | MGI Sequence Detail 3342 C57BL/6  
polypeptide Q9D5L7 UniProt | EBI | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    cDNA 45

    Microarray probesets 9
Other
Accession IDs
less
MGI:1922029, MGI:2140339, MGI:2140398
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:277169 Pfeifer M, et al., SSB1/SSB2 Proteins Safeguard B Cell Development by Protecting the Genomes of B Cell Precursors. J Immunol. 2019 Jun 15;202(12):3423-3433
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory