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Mroh2b Gene Detail
Summary
  • Symbol
    Mroh2b
  • Name
    maestro heat-like repeat family member 2B
  • Synonyms
    4930455B06Rik, Heatr7b2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921905
    NCBI Gene: 223825
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:4928219-4991687 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 1.98 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1808 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921905
 protein coding gene Chr15:4927697-4991689 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021688
 protein coding gene Chr15:1781931-1851901 (+)
A/J MGP_AJ_G0021648
 protein coding gene Chr15:1800868-1862871 (+)
AKR/J MGP_AKRJ_G0021626
 protein coding gene Chr15:1768410-1842015 (+)
BALB/cJ MGP_BALBcJ_G0021655
 protein coding gene Chr15:1736451-1805131 (+)
C3H/HeJ MGP_C3HHeJ_G0021431
 protein coding gene Chr15:1802499-1866667 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022094
 protein coding gene Chr15:1865022-1927761 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019632
 protein coding gene Chr15:1561004-1624489 (+)
CAST/EiJ MGP_CASTEiJ_G0020948
 protein coding gene Chr15:1777625-1838364 (+)
CBA/J MGP_CBAJ_G0021400
 protein coding gene Chr15:1903675-1972083 (+)
DBA/2J MGP_DBA2J_G0021524
 protein coding gene Chr15:1742160-1808081 (+)
FVB/NJ MGP_FVBNJ_G0021502
 protein coding gene Chr15:1686436-1749507 (+)
LP/J MGP_LPJ_G0021592
 protein coding gene Chr15:1724267-1791098 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021528
 protein coding gene Chr15:2022770-2091908 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022117
 protein coding gene Chr15:1787670-1847743 (+)
PWK/PhJ MGP_PWKPhJ_G0020691
 protein coding gene Chr15:1750031-1817641 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020529
 protein coding gene Chr15:1754606-1820200 (+)
WSB/EiJ MGP_WSBEiJ_G0021003
 protein coding gene Chr15:1723831-1792577 (+)



Homology
more
  • Human Ortholog
    MROH2B, maestro heat like repeat family member 2B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH2B, maestro heat like repeat family member 2B
  • Synonyms
    HEATR7B2, SPIF
  • Links
    NCBI Gene ID: 133558
    neXtProt AC: NX_Q7Z745
    UniProt: Q7Z745

  • Chr Location
    5p13.1; chr5:40998017-41071342 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022155 Ensembl Gene Model | MGI Sequence Detail 63469 C57BL/6J ±  kb
transcript ENSMUST00000045736 Ensembl | MGI Sequence Detail 4829 Not Applicable  
polypeptide ENSMUSP00000036148 Ensembl | MGI Sequence Detail 1581 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory