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Spdye4a Gene Detail
Summary
  • Symbol
    Spdye4a
  • Name
    speedy/RINGO cell cycle regulator family, member E4A
  • Synonyms
    4930445A17Rik, 4930451F05Rik, Spdyb, speedy B, speedy/ringo
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921923
    NCBI Gene: 74673
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:143202071-143212645 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 82.01 cM, cytoband G2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    526 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921923
protein coding gene Chr5:143202070-143212657 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030324
protein coding gene Chr5:148535851-148544762 (-)
A/J MGP_AJ_G0030293
protein coding gene Chr5:142159253-142170114 (-)
AKR/J MGP_AKRJ_G0030225
protein coding gene Chr5:146610743-146621648 (-)
BALB/cJ MGP_BALBcJ_G0030310
protein coding gene Chr5:143408449-143420561 (-)
C3H/HeJ MGP_C3HHeJ_G0030021
protein coding gene Chr5:147418409-147436898 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030755
protein coding gene Chr5:153955830-153970779 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027973
protein coding gene Chr5:135939765-135948439 (-)
CAST/EiJ MGP_CASTEiJ_G0029426
protein coding gene Chr5:146910913-146929622 (-)
CBA/J MGP_CBAJ_G0029991
protein coding gene Chr5:160289872-160314210 (-)
DBA/2J MGP_DBA2J_G0030141
protein coding gene Chr5:141927077-141937333 (-)
FVB/NJ MGP_FVBNJ_G0030096
protein coding gene Chr5:141126584-141142448 (-)
LP/J MGP_LPJ_G0030227
protein coding gene Chr5:149130999-149146499 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030127
protein coding gene Chr5:162705808-162715122 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030795
protein coding gene Chr5:146452326-146467535 (-)
PWK/PhJ MGP_PWKPhJ_G0029141
protein coding gene Chr5:141009178-141020392 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028977
protein coding gene Chr5:144197873-144208897 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SPDYE1, speedy/RINGO cell cycle regulator family member E1
  • Vertebrate Orthologs
    11
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPDYE1, speedy/RINGO cell cycle regulator family member E1
  • Synonyms
    Ringo1, SPDYB2L2, SPDYE, WBSCR19
  • Links
    NCBI Gene ID: 285955
    neXtProt AC: NX_Q8NFV5
    UniProt: Q8NFV5

  • Chr Location
    7p13; chr7:43997897-44010124 (+)  GRCh38

  • Human Ortholog
    SPDYE11, speedy/RINGO cell cycle regulator family member E11
  • Links
    NCBI Gene ID: 100996746
    neXtProt AC: NX_P0DTA3
    UniProt: P0DTA3

  • Chr Location
    chr7:73047862-73057911 (-)  GRCh38

  • Human Ortholog
    SPDYE13, speedy/RINGO cell cycle regulator family member E13
  • Synonyms
    SPDYE13P
  • Links
    NCBI Gene ID: 105180390

  • Chr Location
    chr7:75280790-75291806 (+)  GRCh38

  • Human Ortholog
    SPDYE14, speedy/RINGO cell cycle regulator family member E14
  • Synonyms
    SPDYE13, SPDYE14P
  • Links
    NCBI Gene ID: 641776
    UniProt: P0DUD3

  • Chr Location
    7q11.23; chr7:75237205-75317429 (+)  GRCh38

  • Human Ortholog
    SPDYE21, speedy/RINGO cell cycle regulator family member E21
  • Synonyms
    SPDYE21P
  • Links
    NCBI Gene ID: 442572
    UniProt: A0A494C086

  • Chr Location
    chr7:67276941-67289005 (+)  GRCh38

  • Human Ortholog
    SPDYE4, speedy/RINGO cell cycle regulator family member E4
  • Links
    NCBI Gene ID: 388333
    neXtProt AC: NX_A6NLX3
    UniProt: A6NLX3

  • Chr Location
    17p13.1; chr17:8747524-8758559 (-)  GRCh38

  • Human Ortholog
    SPDYE5, speedy/RINGO cell cycle regulator family member E5
  • Links
    NCBI Gene ID: 442590
    neXtProt AC: NX_A6NIY4
    UniProt: A6NIY4

  • Chr Location
    chr7:75491630-75504316 (+)  GRCh38

  • Human Ortholog
    SPDYE7P, speedy/RINGO cell cycle regulator family member E7, pseudogene
  • Links
    NCBI Gene ID: 441251
    UniProt: Q495Y7

  • Chr Location
    7q11.23; chr7:72861524-72873294 (-)  GRCh38

  • Human Ortholog
    SPDYE8, speedy/RINGO cell cycle regulator family member E8
  • Synonyms
    SPDYE8P, SPDYE9
  • Links
    NCBI Gene ID: 728524
    UniProt: P0DUD1

  • Chr Location
    7q11.23; chr7:73019719-73029766 (-)  GRCh38

  • Human Ortholog
    SPDYE9, speedy/RINGO cell cycle regulator family member E9
  • Synonyms
    SPDYE9P
  • Links
    NCBI Gene ID: 643909

  • Chr Location
    7q11.23

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039296 Ensembl Gene Model | MGI Sequence Detail 10575 C57BL/6J ±  kb
transcript ENSMUST00000085733 Ensembl | MGI Sequence Detail 1819 Not Applicable  
polypeptide ENSMUSP00000082882 Ensembl | MGI Sequence Detail 268 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1921245
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:344875 Xu H, et al., Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene. Gen Comp Endocrinol. 2023 Jan 1;330:114148

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory