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Trim14 Gene Detail
Summary
  • Symbol
    Trim14
  • Name
    tripartite motif-containing 14
  • Synonyms
    5830400N10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921985
    NCBI Gene: 74735
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:46505072-46536148 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 24.84 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    843 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921985
 protein coding gene Chr4:46493781-46536148 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028260
 protein coding gene Chr4:44813685-44854983 (-)
A/J MGP_AJ_G0028219
 protein coding gene Chr4:43168920-43204640 (-)
AKR/J MGP_AKRJ_G0028169
 protein coding gene Chr4:44220819-44264789 (-)
BALB/cJ MGP_BALBcJ_G0028239
 protein coding gene Chr4:43270837-43311159 (-)
C3H/HeJ MGP_C3HHeJ_G0027960
 protein coding gene Chr4:44830637-44867358 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028680
 protein coding gene Chr4:46467122-46512778 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025989
 protein coding gene Chr4:40548344-40583781 (-)
CAST/EiJ MGP_CASTEiJ_G0027399
 protein coding gene Chr4:44385368-44429160 (-)
CBA/J MGP_CBAJ_G0027926
 protein coding gene Chr4:47949903-47990835 (-)
DBA/2J MGP_DBA2J_G0028076
 protein coding gene Chr4:43058732-43095565 (-)
FVB/NJ MGP_FVBNJ_G0028043
 protein coding gene Chr4:42307998-42351144 (-)
LP/J MGP_LPJ_G0028175
 protein coding gene Chr4:44864730-44903622 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028067
 protein coding gene Chr4:51021999-51064622 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028715
 protein coding gene Chr4:44442007-44482017 (-)
PWK/PhJ MGP_PWKPhJ_G0027124
 protein coding gene Chr4:43163342-43200724 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026952
 protein coding gene Chr4:43948176-43985237 (-)
WSB/EiJ MGP_WSBEiJ_G0027477
 protein coding gene Chr4:44354420-44400509 (-)



Homology
more
  • Human Ortholog
    TRIM14, tripartite motif containing 14
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM14, tripartite motif containing 14
  • Links
    NCBI Gene ID: 9830
    neXtProt AC: NX_Q14142
    UniProt: Q14142

  • Chr Location
    9q22.33; chr9:98035797-98119222 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are highly susceptible to lethal HSV-1 infection.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    764
  • Tissues
    36
  • cDNA Data
    23
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74735 NCBI Gene Model | MGI Sequence Detail 31077 C57BL/6J ±  kb
transcript NM_029077 RefSeq | MGI Sequence Detail 3204 C57BL/6  
polypeptide Q8BVW3 UniProt | EBI | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 2
    cDNA 23

    Microarray probesets 2
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory