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Rita1 Gene Detail
Summary
  • Symbol
    Rita1
  • Name
    RBPJ interacting and tubulin associated 1
  • Synonyms
    1110008J03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922021
    NCBI Gene: 100764
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:120747123-120750654 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 60.63 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    194 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922021
 protein coding gene Chr5:120732370-120750654 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030008
 protein coding gene Chr5:123978943-123997534 (-)
A/J MGP_AJ_G0029972
 protein coding gene Chr5:118840014-118858272 (-)
AKR/J MGP_AKRJ_G0029911
 protein coding gene Chr5:122675549-122695978 (-)
BALB/cJ MGP_BALBcJ_G0029983
 protein coding gene Chr5:120257554-120275798 (-)
C3H/HeJ MGP_C3HHeJ_G0029703
 protein coding gene Chr5:123211710-123229647 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030438
 protein coding gene Chr5:128632680-128652406 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027664
 protein coding gene Chr5:113549936-113568547 (-)
CAST/EiJ MGP_CASTEiJ_G0029112
 protein coding gene Chr5:122337156-122357264 (-)
CBA/J MGP_CBAJ_G0029671
 protein coding gene Chr5:133624963-133645794 (-)
DBA/2J MGP_DBA2J_G0029821
 protein coding gene Chr5:118925793-118944309 (-)
FVB/NJ MGP_FVBNJ_G0029777
 protein coding gene Chr5:117851748-117871008 (-)
LP/J MGP_LPJ_G0029909
 protein coding gene Chr5:124428329-124454719 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029808
 protein coding gene Chr5:137588598-137610595 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030479
 protein coding gene Chr5:122254342-122273997 (-)
PWK/PhJ MGP_PWKPhJ_G0028825
 protein coding gene Chr5:117686507-117705472 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028664
 protein coding gene Chr5:119914997-119936477 (-)
WSB/EiJ MGP_WSBEiJ_G0029187
 protein coding gene Chr5:122847171-122867279 (-)



Homology
more
  • Human Ortholog
    RITA1, RBPJ interacting and tubulin associated 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RITA1, RBPJ interacting and tubulin associated 1
  • Synonyms
    C12orf52, RITA
  • Links
    NCBI Gene ID: 84934
    neXtProt AC: NX_Q96K30
    UniProt: Q96K30

  • Chr Location
    12q24.13; chr12:113185526-113192368 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100764 NCBI Gene Model | MGI Sequence Detail 3532 C57BL/6J ±  kb
transcript NM_133908 RefSeq | MGI Sequence Detail 1668 C57BL/6  
polypeptide Q9D1H0 UniProt | EBI | MGI Sequence Detail 253 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000060011 RBPJ-interacting and tubulin-associated protein 1
    (term hierarchy)
  • InterPro Domains
    IPR031418 RBPJ-interacting and tubulin-associated protein 1
  • GlyGen
    Q9D1H0 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140999, MGI:2141332
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:339063 Steinhauser K, et al., Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics. Oncogene. 2017 Apr;36(15):2146-2159
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory