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4930503L19Rik Gene Detail
Summary
  • Symbol
    4930503L19Rik
  • Name
    RIKEN cDNA 4930503L19 gene
  • Synonyms
    Las2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922045
    NCBI Gene: 269033
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:70585283-70605580 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 44.42 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    883 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922045
 protein coding gene Chr18:70585281-70605935 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024542
 protein coding gene Chr18:70930517-70951191 (-)
A/J MGP_AJ_G0024509
 protein coding gene Chr18:67817984-67837315 (-)
AKR/J MGP_AKRJ_G0024480
 protein coding gene Chr18:69823095-69842360 (-)
BALB/cJ MGP_BALBcJ_G0024509
 protein coding gene Chr18:67989674-68009071 (-)
C3H/HeJ MGP_C3HHeJ_G0024277
 protein coding gene Chr18:69927493-69947640 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024955
 protein coding gene Chr18:72755302-72775239 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022386
 protein coding gene Chr18:67107449-67127042 (-)
CAST/EiJ MGP_CASTEiJ_G0023750
 protein coding gene Chr18:70042806-70062813 (-)
CBA/J MGP_CBAJ_G0024246
 protein coding gene Chr18:75234600-75256951 (-)
DBA/2J MGP_DBA2J_G0024376
 protein coding gene Chr18:67441253-67460942 (-)
FVB/NJ MGP_FVBNJ_G0024342
 protein coding gene Chr18:66802109-66821591 (-)
LP/J MGP_LPJ_G0024460
 protein coding gene Chr18:70785977-70806134 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024372
 protein coding gene Chr18:76483521-76515250 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025003
 protein coding gene Chr18:69989431-70008742 (-)
PWK/PhJ MGP_PWKPhJ_G0023494
 protein coding gene Chr18:67808393-67828255 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023298
 protein coding gene Chr18:70120826-70140246 (-)
WSB/EiJ MGP_WSBEiJ_G0023813
 protein coding gene Chr18:69925555-69946016 (-)



Homology
more
  • Human Ortholog
    C18orf54, chromosome 18 open reading frame 54
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C18orf54, chromosome 18 open reading frame 54
  • Synonyms
    LAS2
  • Links
    NCBI Gene ID: 162681
    neXtProt AC: NX_Q8IYD9
    UniProt: Q8IYD9

  • Chr Location
    18q21.2; chr18:54357906-54385218 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Variations (SNPs and in-frame insertions and deletions) in the coding region of the gene, observed between different strains, modify the sensitivity or resistance to induced lung adenomas.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    13
  • cDNA Data
    16
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044906 Ensembl Gene Model | MGI Sequence Detail 20298 C57BL/6J ±  kb
transcript ENSMUST00000067556 Ensembl | MGI Sequence Detail 2291 Not Applicable  
polypeptide ENSMUSP00000065118 Ensembl | MGI Sequence Detail 526 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2147388
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:243411 Rutledge EA, et al., Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory