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Tmco5b Gene Detail
Summary
  • Symbol
    Tmco5b
  • Name
    transmembrane and coiled-coil domains 5B
  • Synonyms
    4930563P21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922525
    NCBI Gene: 75275
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:113116077-113127535 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 57.30 cM, cytoband E4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    390 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922525
 protein coding gene Chr2:113115440-113127535 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026295
 protein coding gene Chr2:115762173-115775911 (+)
A/J MGP_AJ_G0026256
 protein coding gene Chr2:111028048-111039655 (+)
AKR/J MGP_AKRJ_G0026235
 protein coding gene Chr2:114133237-114146082 (+)
BALB/cJ MGP_BALBcJ_G0026269
 protein coding gene Chr2:111272851-111285263 (+)
C3H/HeJ MGP_C3HHeJ_G0026014
 protein coding gene Chr2:114541251-114558385 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026716
 protein coding gene Chr2:119578343-119591155 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024096
 protein coding gene Chr2:106223066-106234622 (+)
CAST/EiJ MGP_CASTEiJ_G0025477
 protein coding gene Chr2:114826534-114842209 (+)
CBA/J MGP_CBAJ_G0025991
 protein coding gene Chr2:123774699-123789259 (+)
DBA/2J MGP_DBA2J_G0026130
 protein coding gene Chr2:110502422-110514545 (+)
FVB/NJ MGP_FVBNJ_G0026092
 protein coding gene Chr2:109355600-109366992 (+)
LP/J MGP_LPJ_G0026231
 protein coding gene Chr2:116054415-116067109 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026111
 protein coding gene Chr2:128143330-128162784 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026771
 protein coding gene Chr2:114197240-114213484 (+)
PWK/PhJ MGP_PWKPhJ_G0025213
 protein coding gene Chr2:109999051-110010974 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025012
 protein coding gene Chr2:113358863-113371233 (+)
WSB/EiJ MGP_WSBEiJ_G0025546
 protein coding gene Chr2:115013526-115029625 (+)



Homology
more
  • Human Ortholog
    TMCO5B, transmembrane and coiled-coil domains 5B (pseudogene)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMCO5B, transmembrane and coiled-coil domains 5B (pseudogene)
  • Links
    NCBI Gene ID: 100652857
    UniProt: A8MYB1

  • Chr Location
    chr15:33235755-33247555 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Tmco5b
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    4
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041255 Ensembl Gene Model | MGI Sequence Detail 11459 C57BL/6J ±  kb
transcript ENSMUST00000040856 Ensembl | MGI Sequence Detail 1237 Not Applicable  
polypeptide ENSMUSP00000042247 Ensembl | MGI Sequence Detail 307 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032597 transmembrane and coiled-coil domain-containing protein 5B
    (term hierarchy)
  • InterPro Domains
    IPR026617 Transmembrane and coiled-coil domain-containing protein 2/5
  • GlyGen
    Q80X59 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:123068 Pavel E, et al., Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region. Int J Dev Biol. 2007;51(4):273-81
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory