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Cfap144 Gene Detail
Summary
  • Symbol
    Cfap144
  • Name
    cilia and flagella associated protein 144
  • Synonyms
    3100002J23Rik, Fam183b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922679
    NCBI Gene: 75429
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:58683628-58692786 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 36.30 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    542 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922679
 protein coding gene Chr11:58683623-58692786 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018375
 protein coding gene Chr11:58558098-58567186 (-)
A/J MGP_AJ_G0018344
 protein coding gene Chr11:56286093-56295414 (-)
AKR/J MGP_AKRJ_G0018313
 protein coding gene Chr11:58204072-58213487 (-)
BALB/cJ MGP_BALBcJ_G0018315
 protein coding gene Chr11:56660461-56669525 (-)
C3H/HeJ MGP_C3HHeJ_G0018127
 protein coding gene Chr11:58086306-58098627 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018766
 protein coding gene Chr11:60390996-60401900 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016414
 protein coding gene Chr11:53609390-53619238 (-)
CAST/EiJ MGP_CASTEiJ_G0017688
 protein coding gene Chr11:58190353-58200783 (-)
CBA/J MGP_CBAJ_G0018101
 protein coding gene Chr11:63077144-63086461 (-)
DBA/2J MGP_DBA2J_G0018210
 protein coding gene Chr11:55982074-55991443 (-)
FVB/NJ MGP_FVBNJ_G0018202
 protein coding gene Chr11:55626323-55635650 (-)
LP/J MGP_LPJ_G0018284
 protein coding gene Chr11:59102248-59111504 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018226
 protein coding gene Chr11:64221339-64231326 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018809
 protein coding gene Chr11:58220682-58229935 (-)
PWK/PhJ MGP_PWKPhJ_G0017458
 protein coding gene Chr11:56574287-56583780 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017251
 protein coding gene Chr11:58026495-58038707 (-)
WSB/EiJ MGP_WSBEiJ_G0017738
 protein coding gene Chr11:57890981-57900004 (-)



Homology
more
  • Human Ortholog
    CFAP144, cilia and flagella associated protein 144
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP144, cilia and flagella associated protein 144
  • Synonyms
    FAM183A
  • Links
    NCBI Gene ID: 440585
    neXtProt AC: NX_A6NL82
    UniProt: A6NL82

  • Chr Location
    1p34.2; chr1:43142962-43156396 (+)  GRCh38
  • Human Ortholog
    CFAP144P1, CFAP144 pseudogene 1
  • Synonyms
    FAM183B, FAM183BP, THEG6
  • Links
    NCBI Gene ID: 340286
    UniProt: Q6ZVS7

  • Chr Location
    7p14.1; chr7:38685346-38687089 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a knock-out allele are viable and fertile and do not display any defects indicative of motile ciliary dysfunction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    783
  • Tissues
    35
  • cDNA Data
    16
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 75429 NCBI Gene Model | MGI Sequence Detail 9159 C57BL/6J ±  kb
transcript NM_029283 RefSeq | MGI Sequence Detail 562 C57BL/6  
polypeptide Q5NC57 UniProt | EBI | MGI Sequence Detail 135 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 17
    Primer pair 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:7541309
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory