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Anapc15 Gene Detail
Summary
  • Symbol
    Anapc15
  • Name
    anaphase promoting complex C subunit 15
  • Synonyms
    3200002M19Rik, 6330414C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922680
    NCBI Gene: 75430
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:101530508-101551056 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.68 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    568 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922680
 protein coding gene Chr7:101512922-101551056 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032591
 protein coding gene Chr7:104895302-104917724 (+)
A/J MGP_AJ_G0032567
 protein coding gene Chr7:102224073-102244622 (+)
AKR/J MGP_AKRJ_G0032503
 protein coding gene Chr7:104671503-104691998 (+)
BALB/cJ MGP_BALBcJ_G0032578
 protein coding gene Chr7:101923381-101944179 (+)
C3H/HeJ MGP_C3HHeJ_G0032292
 protein coding gene Chr7:105044900-105065960 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033075
 protein coding gene Chr7:108847853-108869993 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030069
 protein coding gene Chr7:104584576-104608516 (+)
CAST/EiJ MGP_CASTEiJ_G0031618
 protein coding gene Chr7:96597858-96622385 (+)
CBA/J MGP_CBAJ_G0032258
 protein coding gene Chr7:112612488-112639727 (+)
DBA/2J MGP_DBA2J_G0032410
 protein coding gene Chr7:100554717-100576097 (+)
FVB/NJ MGP_FVBNJ_G0032366
 protein coding gene Chr7:100333733-100355668 (+)
LP/J MGP_LPJ_G0032499
 protein coding gene Chr7:106211194-106234766 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032400
 protein coding gene Chr7:113948019-113968881 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033097
 protein coding gene Chr7:103941190-103962612 (+)
PWK/PhJ MGP_PWKPhJ_G0031336
 protein coding gene Chr7:93681979-93688130 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031180
 protein coding gene Chr7:91253108-91260788 (+)
WSB/EiJ MGP_WSBEiJ_G0031735
 protein coding gene Chr7:104627563-104649704 (+)



Homology
more
  • Human Ortholog
    ANAPC15, anaphase promoting complex subunit 15
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANAPC15, anaphase promoting complex subunit 15
  • Synonyms
    APC15, C11orf51, HSPC020
  • Links
    NCBI Gene ID: 25906
    neXtProt AC: NX_P60006
    UniProt: P60006

  • Chr Location
    11q13.4; chr11:72106372-72112780 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    22
  • cDNA Data
    13
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75430 NCBI Gene Model | MGI Sequence Detail 20549 C57BL/6J ±  kb
    transcript NM_027532 RefSeq | MGI Sequence Detail 885 C57BL/6  
    polypeptide P60007 UniProt | EBI | MGI Sequence Detail 132 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 10
    Other
    Accession IDs
    less
    MGI:1917991
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 19
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory