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Cfap126 Gene Detail
Summary
  • Symbol
    Cfap126
  • Name
    cilia and flagella associated protein 126
  • Synonyms
    1700009P17Rik, Flattop, Fltp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922722
    NCBI Gene: 75472
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:170941487-170954536 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 78.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    388 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922722
 protein coding gene Chr1:170941326-170954536 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016741
 protein coding gene Chr1:176888854-176902641 (+)
A/J MGP_AJ_G0016721
 protein coding gene Chr1:169694229-169707760 (+)
AKR/J MGP_AKRJ_G0016687
 protein coding gene Chr1:174771232-174786388 (+)
BALB/cJ MGP_BALBcJ_G0016682
 protein coding gene Chr1:170174411-170189815 (+)
C3H/HeJ MGP_C3HHeJ_G0016505
 protein coding gene Chr1:175022729-175036120 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017143
 protein coding gene Chr1:182772518-182786871 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014851
 protein coding gene Chr1:161372569-161385346 (+)
CAST/EiJ MGP_CASTEiJ_G0016086
 protein coding gene Chr1:174644319-174657063 (+)
CBA/J MGP_CBAJ_G0016480
 protein coding gene Chr1:189274713-189293852 (+)
DBA/2J MGP_DBA2J_G0016587
 protein coding gene Chr1:168533726-168546853 (+)
FVB/NJ MGP_FVBNJ_G0016583
 protein coding gene Chr1:166883876-166896725 (+)
LP/J MGP_LPJ_G0016658
 protein coding gene Chr1:178009351-178024260 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016610
 protein coding gene Chr1:196564591-196582558 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017180
 protein coding gene Chr1:174647014-174661872 (+)
PWK/PhJ MGP_PWKPhJ_G0015872
 protein coding gene Chr1:167752666-167767036 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015656
 protein coding gene Chr1:173435922-173452273 (+)
WSB/EiJ MGP_WSBEiJ_G0016148
 protein coding gene Chr1:174761345-174776751 (+)



Homology
more
  • Human Ortholog
    CFAP126, cilia and flagella associated protein 126
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP126, cilia and flagella associated protein 126
  • Synonyms
    C1orf192, Flattop, Fltp
  • Links
    NCBI Gene ID: 257177
    neXtProt AC: NX_Q5VTH2
    UniProt: Q5VTH2

  • Chr Location
    1q23.3; chr1:161364733-161367876 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Mice homozygous for a knock-in allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    780
  • Tissues
    27
  • cDNA Data
    17
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026649 Ensembl Gene Model | MGI Sequence Detail 13050 C57BL/6J ±  kb
transcript ENSMUST00000129651 Ensembl | MGI Sequence Detail 766 Not Applicable  
polypeptide ENSMUSP00000114967 Ensembl | MGI Sequence Detail 233 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2138531
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:352387 Tai L, et al., In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov. 2023 Nov 21;9(1):116
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory