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Spata45 Gene Detail
Summary
  • Symbol
    Spata45
  • Name
    spermatogenesis associated 45
  • Synonyms
    1700022P22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922808
    NCBI Gene: 75558
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:190768836-190775139 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 96.28 cM, cytoband H6
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922808
protein coding gene Chr1:190768106-190775139 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016936
protein coding gene Chr1:198058035-198064998 (+)
A/J MGP_AJ_G0016915
protein coding gene Chr1:189942020-189948048 (+)
AKR/J MGP_AKRJ_G0016880
protein coding gene Chr1:195560364-195566177 (+)
BALB/cJ MGP_BALBcJ_G0016873
protein coding gene Chr1:190614214-190620960 (+)
C3H/HeJ MGP_C3HHeJ_G0016697
protein coding gene Chr1:196408290-196414221 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017336
protein coding gene Chr1:204364250-204372244 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015043
protein coding gene Chr1:180840938-180846776 (+)
CAST/EiJ MGP_CASTEiJ_G0016280
protein coding gene Chr1:195997325-196003589 (+)
CBA/J MGP_CBAJ_G0016671
protein coding gene Chr1:211931317-211937415 (+)
DBA/2J MGP_DBA2J_G0016777
protein coding gene Chr1:188662169-188668286 (+)
FVB/NJ MGP_FVBNJ_G0016773
protein coding gene Chr1:186787404-186793553 (+)
LP/J MGP_LPJ_G0016852
protein coding gene Chr1:199228319-199234120 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016805
protein coding gene Chr1:218639598-218647073 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017373
protein coding gene Chr1:195446687-195453936 (+)
PWK/PhJ MGP_PWKPhJ_G0016067
protein coding gene Chr1:187942072-187948279 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015843
protein coding gene Chr1:194446544-194452342 (+)
WSB/EiJ MGP_WSBEiJ_G0016342
protein coding gene Chr1:195662046-195669887 (+)



Homology
more
  • Human Ortholog
    SPATA45, spermatogenesis associated 45
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPATA45, spermatogenesis associated 45
  • Synonyms
    C1orf227
  • Links
    NCBI Gene ID: 149643
    neXtProt AC: NX_Q537H7
    UniProt: Q537H7

  • Chr Location
    1q32.3; chr1:212830141-212847649 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Male mice for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000057072 Ensembl Gene Model | MGI Sequence Detail 6304 C57BL/6J ±  kb
    transcript ENSMUST00000192151 Ensembl | MGI Sequence Detail 443 Not Applicable  
    polypeptide ENSMUSP00000141721 Ensembl | MGI Sequence Detail 97 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 5
    References
    more
    • Summaries
      All 19
      Phenotypes 2
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:348435 Suzuki A, et al., Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice. J Reprod Immunol. 2024;:104252

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    10/29/2024
    MGI 6.24
    The Jackson Laboratory