Snapc1 MGI Mouse Gene Detail - MGI:1922877 - small nuclear RNA activating complex, polypeptide 1

Symbol

Snapc1
Name

small nuclear RNA activating complex, polypeptide 1
Synonyms

2700033G17Rik, 9630050P21Rik

Feature Type

protein coding gene
IDs

MGI:1922877
NCBI Gene: 75627
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr12:74011255-74035740 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 32.00 cM
Mapping Data

2 experiments

SNPs within 2kb

812 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922877	protein coding gene	Chr12:74011255-74035836 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019841	protein coding gene	Chr12:73910685-73934057 (+)
A/J	MGP_AJ_G0019799	protein coding gene	Chr12:71136517-71163677 (+)
AKR/J	MGP_AKRJ_G0019774	protein coding gene	Chr12:73282010-73303144 (+)
BALB/cJ	MGP_BALBcJ_G0019779	protein coding gene	Chr12:71615996-71637096 (+)
C3H/HeJ	MGP_C3HHeJ_G0019584	protein coding gene	Chr12:73745342-73765450 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020231	protein coding gene	Chr12:76186814-76208495 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017849	protein coding gene	Chr12:68576048-68597108 (+)
CAST/EiJ	MGP_CASTEiJ_G0019136	protein coding gene	Chr12:68530278-68552170 (+)
CBA/J	MGP_CBAJ_G0019554	protein coding gene	Chr12:79132489-79155291 (+)
DBA/2J	MGP_DBA2J_G0019670	protein coding gene	Chr12:71023739-71043862 (+)
FVB/NJ	MGP_FVBNJ_G0019657	protein coding gene	Chr12:69867210-69888252 (+)
LP/J	MGP_LPJ_G0019742	protein coding gene	Chr12:73922631-73943655 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019696	protein coding gene	Chr12:82212908-82235579 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020266	protein coding gene	Chr12:72776934-72797890 (+)
PWK/PhJ	MGP_PWKPhJ_G0018901	protein coding gene	Chr12:65351137-65373259 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018696	protein coding gene	Chr12:67213850-67237538 (+)
WSB/EiJ	MGP_WSBEiJ_G0019187	protein coding gene	Chr12:73373214-73394844 (+)

Human Ortholog

SNAPC1, small nuclear RNA activating complex polypeptide 1

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SNAPC1, small nuclear RNA activating complex polypeptide 1
Synonyms

PTFgamma, SNAP43
Links

HGNC:11134

NCBI Gene ID: 6617

neXtProt AC: NX_Q16533

UniProt: Q16533
Chr Location

14q23.2; chr14:61762420-61796428 (+) GRCh38

MGI Vertebrate Homology

Snapc1 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: SNAPC1
Gene Tree

Snapc1

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Phenotype Summary

5 phenotypes from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Chemically induced (other)

1
Gene trapped

3
Targeted

5
Genomic Mutations

1 involving Snapc1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

34 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

9
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

774
Tissues

46
cDNA Data

13
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase snapc1

ZFIN snapc1a, snapc1b

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All Sequences

63
RefSeq

12
UniProt

5
CCDS

CCDS25978.1

Ensembl

ENSMUSG00000021113 (Evidence)
NCBI Gene

75627

			Length	Strain/Species	Flank
genomic	ENSMUSG00000021113	Ensembl Gene Model \| MGI Sequence Detail	24486	C57BL/6J	± kb
transcript	ENSMUST00000021532	Ensembl \| MGI Sequence Detail	6275	Not Applicable
polypeptide	ENSMUSP00000021532	Ensembl \| MGI Sequence Detail	389	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000015316 snRNA-activating protein complex subunit 1

(term hierarchy)
InterPro Domains

IPR019188 snRNA-activating protein complex subunit 1

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All nucleic 13

cDNA 13

Microarray probesets 5

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MGI:2144937, MGI:2442994

Summaries

All 37

Developmental Gene Expression 2

Gene Ontology 4

Phenotypes 11
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Snapc1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr113876	Chr12:74011255-74011316 (+)	31 bp
Tssr113877	Chr12:74011318-74011337 (+)	73 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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